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Drug Interactions between faricimab ophthalmic and sorafenib

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

SORAfenib faricimab ophthalmic

Applies to: sorafenib and faricimab ophthalmic

Consumer information for this interaction is not currently available.

GENERALLY AVOID: Coadministration of ophthalmic faricimab with other anti-vascular endothelial growth factor (VEGF) and/or other therapies (e.g., photodynamic therapy) for the treatment of neovascular (wet) age-related macular degeneration (nAMD), visual impairment due to diabetic macular edema (DMO), and/or visual impairment due to macular edema secondary to retinal vein occlusion (RVO) in the same eye has not been evaluated.

MANAGEMENT: According to some authorities, concomitant use of ophthalmic faricimab with other anti-VEGF products, systemic or ocular, and/or other therapies (e.g., photodynamic therapies) in the same eye should generally be avoided. Clinical data characterizing the extent of this interaction are not available. Consultation with package labeling and relevant institutional protocols may be advisable for further guidance.

Drug and food/lifestyle interactions

Moderate

SORAfenib food/lifestyle

Applies to: sorafenib

You may experience reduced absorption of SORAfenib in the presence of food. Take SORAfenib on an empty stomach 1 hour before or 2 hours after a meal unless otherwise directed by your doctor. This will make it easier for your body to absorb the medication.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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