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Drug Interactions between carboplatin and sorafenib

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

CARBOplatin SORAfenib

Applies to: carboplatin and sorafenib

If you are receiving CARBOplatin and SORAfenib together with paclitaxel, you should talk to your doctor to make sure this treatment is appropriate for your condition. When used in the treatment of a specific type of lung cancer known as squamous cell carcinoma, this three drug combination has been associated with an increased rate of death compared to treatment with CARBOplatin plus paclitaxel alone. The reason for this is not clear. It is also uncertain whether these medications may have the same effect in some other types of cancer. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

Moderate

SORAfenib food

Applies to: sorafenib

You may experience reduced absorption of SORAfenib in the presence of food. Take SORAfenib on an empty stomach 1 hour before or 2 hours after a meal unless otherwise directed by your doctor. This will make it easier for your body to absorb the medication.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer