Paroxetine Drug Interactions
Currently displaying a list of 510 drugs known to interact with paroxetine.
- 106 major drug interactions
- 388 moderate drug interactions
- 16 minor drug interactions
Medications known to interact with paroxetine
Note: Showing generic names only.
5
A
- abciximab
- abiraterone
- abrocitinib
- acalabrutinib
- acetazolamide
- acetohexamide
- acetylcarbromal
- acrivastine
- adagrasib
- ado-trastuzumab emtansine
- aldesleukin
- alfentanil
- allopurinol
- almotriptan
- alprazolam
- alteplase
- amifampridine
- amiloride
- amitriptyline
- amobarbital
- amoxapine
- amphetamine
- anagrelide
- anisindione
- anistreplase
- antithrombin (recombinant)
- antithrombin iii
- apixaban
- apraclonidine ophthalmic
- aprepitant
- ardeparin
- argatroban
- aripiprazole
- asenapine
- aspirin
- astemizole
- atomoxetine
- avapritinib
- azatadine
B
- baclofen
- bendroflumethiazide
- benzgalantamine
- benzphetamine
- benzthiazide
- benztropine
- berotralstat
- betrixaban
- biperiden
- bismuth subsalicylate
- bivalirudin
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromfenac
- bromocriptine
- brompheniramine
- bumetanide
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabozantinib
- cangrelor
- cannabidiol
- cannabis
- capivasertib
- caplacizumab
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- carvedilol
- celecoxib
- cenobamate
- cetirizine
- cevimeline
- chlophedianol
- chloral hydrate
- chlordiazepoxide
- chlormezanone
- chlorothiazide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorpropamide
- chlorthalidone
- chlorzoxazone
- choline salicylate
- cilostazol
- cimetidine
- cinacalcet
- citalopram
- clarithromycin
- clemastine
- clobazam
- clomipramine
- clonazepam
- clopidogrel
- clorazepate
- clozapine
- cobicistat
- codeine
- cyclizine
- cyclobenzaprine
- cyproheptadine
D
- dabigatran
- dacomitinib
- dalteparin
- danaparoid
- dantrolene
- daridorexant
- darifenacin
- darunavir
- dasatinib
- deferasirox
- defibrotide
- desipramine
- desirudin
- desmopressin
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexfenfluramine
- dexmedetomidine
- dexmethylphenidate
- dextroamphetamine
- dextromethorphan
- dezocine
- diazepam
- dichlorphenamide
- diclofenac
- dicumarol
- diethylpropion
- difelikefalin
- diflunisal
- digoxin
- dihydroergotamine
- dimenhydrinate
- diphenhydramine
- dipyridamole
- divalproex sodium
- dolasetron
- donepezil
- doxepin
- doxepin topical
- doxylamine
- dronabinol
- dronedarone
- droperidol
- drotrecogin alfa
- duloxetine
E
- edoxaban
- efavirenz
- eletriptan
- eliglustat
- eluxadoline
- enoxaparin
- entacapone
- eplerenone
- epoprostenol
- eptifibatide
- ergotamine
- erythromycin
- escitalopram
- eslicarbazepine
- estazolam
- eszopiclone
- ethacrynic acid
- ethanol
- ethosuximide
- ethotoin
- etodolac
- evening primrose
- ezogabine
F
- felbamate
- fenfluramine
- fenoprofen
- fentanyl
- fesoterodine
- flavoxate
- flecainide
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- flurbiprofen
- fluvoxamine
- fondaparinux
- fosamprenavir
- fosaprepitant
- frovatriptan
- furazolidone
- furosemide
G
- gabapentin
- gabapentin enacarbil
- galantamine
- ganaxolone
- gepirone
- gilteritinib
- ginkgo
- givosiran
- glimepiride
- glipizide
- glyburide
- glycerol phenylbutyrate
- granisetron
H
- halazepam
- haloperidol
- heparin
- heroin
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxyzine
I
- ibritumomab
- ibrutinib
- ibuprofen
- ifosfamide
- iloperidone
- iloprost
- imatinib
- imipramine
- indapamide
- indomethacin
- inotersen
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- iobenguane I 123
- iodine i 131 tositumomab
- ioflupane I 123
- iohexol
- iomeprol
- iopamidol
- isocarboxazid
- isoniazid
K
L
- labetalol
- lacosamide
- lamotrigine
- lasmiditan
- lemborexant
- lepirudin
- levetiracetam
- levocetirizine
- levodopa
- levomethadyl acetate
- levomilnacipran
- levorphanol
- lidocaine
- lindane topical
- linezolid
- lisdexamfetamine
- lithium
- lofexidine
- lorazepam
- lorcaserin
- loxapine
- lumateperone
- lurasidone
M
- ma huang
- magnesium salicylate
- mannitol
- maprotiline
- mavorixafor
- mazindol
- meclofenamate
- mefenamic acid
- melatonin
- meloxicam
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methamphetamine
- methazolamide
- methdilazine
- methocarbamol
- methohexital
- methotrimeprazine
- methsuximide
- methyclothiazide
- methylene blue
- methylphenidate
- methysergide maleate
- metoclopramide
- metolazone
- metoprolol
- metrizamide
- metyrosine
- mexiletine
- mibefradil
- midazolam
- milnacipran
- mirabegron
- mirtazapine
- mitotane
- molindone
- morphine
- morphine liposomal
N
- nabilone
- nabumetone
- nalbuphine
- naproxen
- naratriptan
- nateglinide
- nebivolol
- nefazodone
- nilotinib
- nitisinone
- nortriptyline
O
- olanzapine
- oliceridine
- olopatadine nasal
- ondansetron
- opicapone
- opium
- oritavancin
- orphenadrine
- oxaprozin
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
- ozanimod
P
- paliperidone
- palonosetron
- panobinostat
- paraldehyde
- paramethadione
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- phenacemide
- phendimetrazine
- phenelzine
- phenobarbital
- phensuximide
- phentermine
- phenylbutazone
- phenylpropanolamine
- phenytoin
- pimozide
- pirfenidone
- piroxicam
- pitolisant
- plasminogen, human
- plicamycin
- polyethylene glycol 3350 with electrolytes
- polythiazide
- ponatinib
- porfimer
- pramipexole
- prasugrel
- pravastatin
- pregabalin
- primidone
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propafenone
- propiomazine
- propoxyphene
- propranolol
- protein c
- protriptyline
- pyrilamine
Q
R
- ramelteon
- ramucirumab
- ranolazine
- rasagiline
- regorafenib
- remifentanil
- remimazolam
- repaglinide
- reteplase
- risperidone
- ritonavir
- rivaroxaban
- rizatriptan
- rolapitant
- ropinirole
- rotigotine
- rufinamide
- ruxolitinib
S
- safinamide
- salsalate
- scopolamine
- secobarbital
- selegiline
- sertraline
- sibutramine
- sodium oxybate
- sodium salicylate
- sodium thiosalicylate
- sofpironium topical
- spironolactone
- st. john's wort
- stiripentol
- streptokinase
- sufentanil
- sulfinpyrazone
- sulindac
- sumatriptan
- suvorexant
T
- tamoxifen
- tamsulosin
- tapentadol
- tasimelteon
- tazemetostat
- tedizolid
- temazepam
- tenecteplase
- terbinafine
- terfenadine
- tetrabenazine
- thalidomide
- thiethylperazine
- thiopental
- thioridazine
- thiothixene
- tiagabine
- ticagrelor
- ticlopidine
- timolol
- timolol ophthalmic
- tinzaparin
- tirofiban
- tizanidine
- tolazamide
- tolbutamide
- tolcapone
- tolmetin
- tolterodine
- topiramate
- torsemide
- tositumomab
- tovorafenib
- tramadol
- tranylcypromine
- trazodone
- treprostinil
- triamterene
- triazolam
- trichlormethiazide
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- troleandomycin
- tryptophan
- turmeric
U
V
- valbenazine
- valerian
- valproic acid
- vasopressin
- vemurafenib
- venlafaxine
- vigabatrin
- vilazodone
- viloxazine
- vorapaxar
- vortioxetine
W
Z
Paroxetine alcohol/food interactions
There is 1 alcohol/food interaction with paroxetine.
Paroxetine disease interactions
There are 11 disease interactions with paroxetine which include:
- depression
- bone fractures
- renal dysfunction
- hyponatremia
- glaucoma
- liver disease
- mania
- platelet function
- seizure disorders
- SIADH
- weight loss
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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