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Prilosec OTC (omeprazole) Drug Interactions

A total of 339 drugs (1989 brand and generic names) are known to interact with Prilosec OTC (omeprazole).

  • 22 major drug interactions (53 brand and generic names)
  • 200 moderate drug interactions (1352 brand and generic names)
  • 117 minor drug interactions (584 brand and generic names)

Show all medications in the database that may interact with Prilosec OTC (omeprazole).

Check for interactions with Prilosec OTC (omeprazole)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Prilosec OTC (omeprazole)

Prilosec OTC (omeprazole) disease Interactions

There are 2 disease interactions with Prilosec OTC (omeprazole) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.