Ketamine Drug Interactions
Currently displaying a list of 424 drugs known to interact with ketamine.
- 216 major drug interactions
- 207 moderate drug interactions
- 1 minor drug interaction
Medications known to interact with ketamine
Note: Showing generic names only.
- abametapir topical
- acetylcarbromal
- adagrasib
- albiglutide
- albuterol
- alfentanil
- alpelisib
- alprazolam
- amantadine
- aminophylline
- amiodarone
- amitriptyline
- amobarbital
- amoxapine
- amphetamine
- apomorphine
- apraclonidine ophthalmic
- arformoterol
- aripiprazole
- armodafinil
- asciminib
- asenapine
- atomoxetine
- atracurium
- avacopan
- azatadine
- azelastine nasal
- baclofen
- belzutifan
- benzphetamine
- benztropine
- biperiden
- bitolterol
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
- bupivacaine
- bupivacaine liposome
- buprenorphine
- buspirone
- butabarbital
- butalbital
- butorphanol
- cannabidiol
- cannabis
- capivasertib
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- cenobamate
- cetirizine
- chlophedianol
- chloral hydrate
- chlordiazepoxide
- chlormezanone
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorzoxazone
- cisatracurium
- citalopram
- clemastine
- clobazam
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- cocaine nasal
- cocaine topical
- codeine
- cyclizine
- cyclobenzaprine
- cyproheptadine
- dabrafenib
- dantrolene
- daridorexant
- darunavir
- deserpidine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexmedetomidine
- dexmethylphenidate
- dextroamphetamine
- dextromethorphan
- dezocine
- diazepam
- diethylpropion
- difelikefalin
- dihydroergotamine
- dimenhydrinate
- diphenhydramine
- dipivefrin ophthalmic
- divalproex sodium
- dobutamine
- dopamine
- doxacurium
- doxapram
- doxepin
- doxepin topical
- doxylamine
- dronabinol
- droperidol
- droxidopa
- dulaglutide
- duloxetine
- duvelisib
- dyphylline
- echinacea
- entacapone
- ephedrine
- ephedrine nasal
- epinephrine
- epinephrine ophthalmic
- epinephrine topical
- ergonovine
- ergotamine
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- eszopiclone
- ethanol
- ethosuximide
- ethotoin
- exenatide
- ezogabine
- felbamate
- fenfluramine
- fenoldopam
- fentanyl
- fexinidazole
- flavoxate
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- formoterol
- fosphenytoin
- fospropofol
- fostamatinib
- furazolidone
- idelalisib
- iloperidone
- imipramine
- indacaterol
- ioflupane I 123
- isavuconazonium
- isocarboxazid
- isoetharine
- isoproterenol
- ivosidenib
- lacosamide
- lamotrigine
- larotrectinib
- lazertinib
- lefamulin
- lemborexant
- lenacapavir
- letermovir
- levalbuterol
- levetiracetam
- levmetamfetamine nasal
- levobupivacaine
- levocetirizine
- levodopa
- levomethadyl acetate
- levomilnacipran
- levorphanol
- levothyroxine
- levothyroxine / liothyronine
- lidocaine
- linezolid
- liothyronine
- liotrix
- liraglutide
- lisdexamfetamine
- lithium
- lixisenatide
- lofexidine
- lonafarnib
- lonapegsomatropin
- lorazepam
- lorlatinib
- loxapine
- lumateperone
- lurasidone
- ma huang
- maprotiline
- mavacamten
- mavorixafor
- mazindol
- mecamylamine
- meclizine
- melatonin
- memantine
- meperidine
- mephentermine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaproterenol
- metaraminol
- metaxalone
- methadone
- methamphetamine
- methdilazine
- methocarbamol
- methotrimeprazine
- methoxamine
- methsuximide
- methyldopa
- methylene blue
- methylergonovine
- methylphenidate
- methysergide maleate
- metoclopramide
- metocurine
- metyrosine
- midazolam
- midodrine
- mifepristone
- milnacipran
- mirtazapine
- mitapivat
- mitotane
- mivacurium
- modafinil
- molindone
- morphine
- morphine liposomal
- nabilone
- nalbuphine
- naphazoline nasal
- naphazoline ophthalmic
- nefazodone
- norepinephrine
- nortriptyline
- olanzapine
- olaparib
- oliceridine
- olodaterol
- olopatadine nasal
- olutasidenib
- omaveloxolone
- opicapone
- opium
- orphenadrine
- osilodrostat
- oxazepam
- oxcarbazepine
- oxtriphylline
- oxycodone
- oxymetazoline nasal
- oxymetazoline ophthalmic
- oxymetazoline topical
- oxymorphone
- ozanimod
- pacritinib
- paliperidone
- pancuronium
- paraldehyde
- paramethadione
- paroxetine
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- pexidartinib
- phenacemide
- phendimetrazine
- phenelzine
- phenindamine
- phenobarbital
- phensuximide
- phentermine
- phenylephrine
- phenylephrine nasal
- phenylephrine ophthalmic
- phenylephrine topical
- phenylpropanolamine
- phenytoin
- pimozide
- pipecuronium
- pirbuterol
- pirtobrutinib
- pitolisant
- pralsetinib
- pramipexole
- pregabalin
- primidone
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propiomazine
- propofol
- propoxyphene
- propylhexedrine nasal
- protriptyline
- pseudoephedrine
- pyrilamine
- racepinephrine
- ramelteon
- rapacuronium
- rasagiline
- rauwolfia serpentina
- remifentanil
- remimazolam
- repotrectinib
- reserpine
- ribociclib
- risperidone
- ritlecitinib
- ritodrine
- rocuronium
- ropinirole
- ropivacaine
- rotigotine
- rucaparib
- rufinamide
- safinamide
- salmeterol
- scopolamine
- secobarbital
- selegiline
- selpercatinib
- semaglutide
- sertraline
- sibutramine
- sodium oxybate
- solriamfetol
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotorasib
- sparsentan
- st. john's wort
- stiripentol
- succinylcholine
- sufentanil
- suvorexant
- suzetrigine
- tapentadol
- tasimelteon
- telotristat
- temazepam
- terbutaline
- tetrabenazine
- tetrahydrozoline nasal
- tetrahydrozoline ophthalmic
- thalidomide
- theophylline
- thiethylperazine
- thiopental
- thioridazine
- thiothixene
- thyroid desiccated
- thyrotropin alpha
- tiagabine
- tirzepatide
- tizanidine
- tolcapone
- topiramate
- tramadol
- tranylcypromine
- trazodone
- triazolam
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- trofinetide
- tubocurarine
- tucatinib
- vadadustat
- valbenazine
- valerian
- valproic acid
- vasopressin
- vecuronium
- venlafaxine
- vigabatrin
- vorasidenib
Ketamine alcohol/food interactions
There are 2 alcohol/food interactions with ketamine.
Ketamine disease interactions
There are 2 disease interactions with ketamine which include:
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.