Lunesta Interactions
There are 386 drugs known to interact with Lunesta (eszopiclone), along with 3 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 54 are major, 331 are moderate, and 1 is minor.
- View all 386 medications that may interact with Lunesta
- View Lunesta alcohol/food interactions (1)
- View Lunesta disease interactions (3)
Most frequently checked interactions
View interaction reports for Lunesta (eszopiclone) and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- atorvastatin
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- gabapentin
- hydroxyzine
- ibuprofen
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- levothyroxine
- Lexapro (escitalopram)
- lisinopril
- Lyrica (pregabalin)
- melatonin
- metformin
- omeprazole
- prednisone
- propranolol
- Seroquel (quetiapine)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Lunesta alcohol/food interactions
There is 1 alcohol/food interaction with Lunesta (eszopiclone).
Lunesta disease interactions
There are 3 disease interactions with Lunesta (eszopiclone) which include:
More about Lunesta (eszopiclone)
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- Side effects
- Dosage information
- During pregnancy
- Generic availability
- Support group
- FDA approval history
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Doxylamine
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Temazepam
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Doxepin
Doxepin is used for anxiety, depression, insomnia, irritable bowel syndrome, major depressive ...
Zolpidem
Zolpidem is a sedative-hypnotic medicine used for the short-term treatment of insomnia (trouble ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.