Lunesta Interactions
There are 378 drugs known to interact with Lunesta (eszopiclone), along with 3 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 54 are major, 322 are moderate, and 2 are minor.
- View all 378 medications that may interact with Lunesta
- View Lunesta alcohol/food interactions (1)
- View Lunesta disease interactions (3)
Most frequently checked interactions
View interaction reports for Lunesta (eszopiclone) and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- gabapentin
- hydroxyzine
- ibuprofen
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- levothyroxine
- Lexapro (escitalopram)
- lisinopril
- Lyrica (pregabalin)
- melatonin
- metformin
- omeprazole
- prednisone
- propranolol
- Seroquel (quetiapine)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Lunesta alcohol/food interactions
There is 1 alcohol/food interaction with Lunesta (eszopiclone).
Lunesta disease interactions
There are 3 disease interactions with Lunesta (eszopiclone) which include:
More about Lunesta (eszopiclone)
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- Side effects
- Dosage information
- During pregnancy
- Generic availability
- Support group
- FDA approval history
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.