Lunesta Drug Interactions
Currently displaying a list of 386 drugs known to interact with Lunesta (eszopiclone).
- 54 major drug interactions
- 331 moderate drug interactions
- 1 minor drug interaction
Medications known to interact with Lunesta
Note: Showing generic names only.
A
- abametapir topical
- acetylcarbromal
- acrivastine
- adagrasib
- aldesleukin
- alfentanil
- allopurinol
- alprazolam
- aminoglutethimide
- amitriptyline
- amobarbital
- amoxapine
- amprenavir
- apalutamide
- apomorphine
- apraclonidine ophthalmic
- aprepitant
- aripiprazole
- armodafinil
- asciminib
- asenapine
- atazanavir
- avacopan
- azatadine
- azelastine nasal
B
- baclofen
- belzutifan
- benztropine
- berotralstat
- bexarotene
- bicalutamide
- biperiden
- boceprevir
- bosentan
- brexanolone
- brexpiprazole
- brigatinib
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cannabidiol
- cannabis
- capivasertib
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- cenobamate
- ceritinib
- cetirizine
- chlophedianol
- chloral hydrate
- chloramphenicol
- chlordiazepoxide
- chlormezanone
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorzoxazone
- ciprofloxacin
- citalopram
- clarithromycin
- clemastine
- clobazam
- clofazimine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clotrimazole
- clozapine
- cobicistat
- codeine
- conivaptan
- crizotinib
- cyclizine
- cyclobenzaprine
- cyproheptadine
D
- dabrafenib
- dantrolene
- daridorexant
- darunavir
- dasatinib
- deferasirox
- delavirdine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexamethasone
- dexbrompheniramine
- dexchlorpheniramine
- dexmedetomidine
- dextromethorphan
- dezocine
- diazepam
- difelikefalin
- diltiazem
- dimenhydrinate
- diphenhydramine
- divalproex sodium
- doxepin
- doxepin topical
- doxylamine
- dronabinol
- dronedarone
- droperidol
- duloxetine
- duvelisib
E
- echinacea
- efavirenz
- elafibranor
- elagolix
- encorafenib
- entacapone
- enzalutamide
- erythromycin
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- ethanol
- ethchlorvynol
- ethosuximide
- ethotoin
- etravirine
- ezogabine
F
- fedratinib
- felbamate
- fenfluramine
- fentanyl
- fexinidazole
- flavoxate
- flibanserin
- fluconazole
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fospropofol
- fostamatinib
G
H
I
- idelalisib
- ifosfamide
- iloperidone
- imatinib
- imipramine
- indinavir
- iptacopan
- isavuconazonium
- isocarboxazid
- isoniazid
- itraconazole
- ivacaftor
- ivosidenib
K
L
- lamotrigine
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- lemborexant
- lenacapavir
- lesinurad
- letermovir
- levetiracetam
- levocetirizine
- levodopa
- levoketoconazole
- levomethadyl acetate
- levorphanol
- lidocaine
- lithium
- lofexidine
- lonafarnib
- lonapegsomatropin
- lorazepam
- lorlatinib
- loxapine
- lumateperone
- lurasidone
M
- maprotiline
- mavacamten
- mavorixafor
- meclizine
- melatonin
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methdilazine
- methocarbamol
- methohexital
- methsuximide
- metoclopramide
- metyrosine
- mibefradil
- miconazole
- midazolam
- mifepristone
- mirtazapine
- mitapivat
- mitotane
- mobocertinib
- modafinil
- molindone
- morphine
- morphine liposomal
N
O
- olanzapine
- oliceridine
- olopatadine nasal
- olutasidenib
- omaveloxolone
- opicapone
- opium
- oritavancin
- orphenadrine
- osilodrostat
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
P
- pacritinib
- paliperidone
- paraldehyde
- paramethadione
- paroxetine
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- pexidartinib
- phenacemide
- phenelzine
- phenindamine
- phenobarbital
- phensuximide
- phenylbutazone
- phenytoin
- pimozide
- pirtobrutinib
- pitolisant
- posaconazole
- pralsetinib
- pramipexole
- pregabalin
- primidone
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propiomazine
- propofol
- propoxyphene
- protriptyline
- pyrilamine
Q
R
- ramelteon
- rasagiline
- remdesivir
- remifentanil
- remimazolam
- repotrectinib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- risperidone
- ritlecitinib
- ritonavir
- ropeginterferon alfa-2b
- ropinirole
- rotigotine
- rucaparib
- rufinamide
S
- safinamide
- saquinavir
- scopolamine
- secobarbital
- selegiline
- selpercatinib
- sertraline
- sibutramine
- sodium oxybate
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotorasib
- st. john's wort
- stiripentol
- sufentanil
- sulfinpyrazone
- suvorexant
- suzetrigine
T
- tapentadol
- tasimelteon
- tazemetostat
- tecovirimat
- telaprevir
- telithromycin
- telotristat
- temazepam
- tetrabenazine
- thalidomide
- thiethylperazine
- thiopental
- thioridazine
- thiothixene
- tiagabine
- tizanidine
- tolcapone
- tolterodine
- topiramate
- tovorafenib
- tramadol
- tranylcypromine
- trazodone
- triazolam
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- trofinetide
- troglitazone
- troleandomycin
- tucatinib
V
- vadadustat
- valbenazine
- valerian
- valproic acid
- vemurafenib
- venlafaxine
- verapamil
- vigabatrin
- vorasidenib
- voriconazole
- voxelotor
Z
Lunesta alcohol/food interactions
There is 1 alcohol/food interaction with Lunesta (eszopiclone).
Lunesta disease interactions
There are 3 disease interactions with Lunesta (eszopiclone) which include:
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More about Lunesta (eszopiclone)
- Lunesta consumer information
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- Reviews (342)
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- During pregnancy
- Generic availability
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- FDA approval history
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
