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Drug Interactions between fluconazole and Lunesta

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

fluconazole eszopiclone

Applies to: fluconazole and Lunesta (eszopiclone)

Fluconazole may increase the blood levels of eszopiclone. In some cases, this can increase the risk of side effects including daytime drowsiness, motor impairment, amnesia, anxiety, abnormal thinking, hallucinations, behavioral changes, and breathing difficulties (especially if you have a respiratory disorder such as asthma or obstructive sleep apnea). You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Talk to your doctor if you have any questions or concerns. You should avoid the use of alcohol while being treated with eszopiclone. Avoid driving or operating hazardous machinery until you know how the medication affects you, and do not exceed the dosage or frequency of use prescribed by your doctor. Because there may be some residual effects of eszopiclone the day after you take it, it may be advisable to wait at least 12 hours after dosing to drive or operate machinery, even when you may feel fully awake. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

eszopiclone food

Applies to: Lunesta (eszopiclone)

Taking eszopiclone with a high-fat or heavy meal may delay the onset of sleep. For faster sleep onset, eszopiclone should not be administered with or immediately after a high-fat or heavy meal. This will make it easier for your body to absorb the medication. You should avoid the use of alcohol while being treated with eszopiclone. Alcohol can increase the nervous system side effects of eszopiclone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Talk to your doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer