Drug Interactions between diclofenac and Spectracef
This report displays the potential drug interactions for the following 2 drugs:
- diclofenac
- Spectracef (cefditoren)
Interactions between your drugs
No interactions were found between diclofenac and Spectracef. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
diclofenac
A total of 422 drugs are known to interact with diclofenac.
- Diclofenac is in the drug class Nonsteroidal anti-inflammatory drugs.
- Diclofenac is used to treat the following conditions:
Spectracef
A total of 48 drugs are known to interact with Spectracef.
- Spectracef is in the drug class third generation cephalosporins.
- Spectracef is used to treat the following conditions:
Drug and food interactions
cefditoren food
Applies to: Spectracef (cefditoren)
ADJUST DOSING INTERVAL: Food enhances the oral absorption and bioavailability of cefditoren pivoxil. According to the manufacturer, administration of cefditoren pivoxil following a high-fat meal increased the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) by 50% and 70%, respectively, compared to administration in the fasting state. The absolute bioavailability of cefditoren pivoxil is approximately 14% under fasting conditions and 16% when given with a low-fat meal.
MANAGEMENT: To ensure maximal oral absorption, cefditoren pivoxil should be administered with or immediately after a meal.
References
- (2001) "Product Information. Spectracef (cefditoren)." TAP Pharmaceuticals Inc
diclofenac food
Applies to: diclofenac
GENERALLY AVOID: The concurrent use of aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) and ethanol may lead to gastrointestinal (GI) blood loss. The mechanism may be due to a combined local effect as well as inhibition of prostaglandins leading to decreased integrity of the GI lining.
MANAGEMENT: Patients should be counseled on this potential interaction and advised to refrain from alcohol consumption while taking aspirin or NSAIDs.
References
- (2002) "Product Information. Motrin (ibuprofen)." Pharmacia and Upjohn
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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