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Verquvo

Generic Name: vericiguat
Dosage Form: tablets

Medically reviewed by Judith Stewart, BPharm. Last updated on Jan 21, 2021.

What is Verquvo?

Verquvo is a prescription medicine used in adults who are having symptoms of their chronic (long-lasting) heart failure, who have had a recent hospitalization or the need to receive intravenous (IV) medicines and have an ejection fraction (amount of blood pumped with each heartbeat) of less than 45 percent:

  • to reduce the risk of dying and
  • to reduce the need to be hospitalized

Heart failure happens when your heart is weak and cannot pump enough blood to your lungs and the rest of your body.
It is not known if this medicine is safe and effective in children.

Warnings

Verquvo may cause birth defects if taken during pregnancy.

  • Females must not be pregnant when they start treatment.
  • Females who are able to get pregnant:
    • Your healthcare provider will do a pregnancy test to make sure that you are not pregnant before you start treatment.
    • You must use effective forms of birth control during treatment and for 1 month after you stop treatment. Talk to your healthcare provider about forms of birth control that you may use to prevent pregnancy during treatment.
    • Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment.

Who should not take Verquvo?

Do not take Verquvo if you:

  • are taking another medicine called a soluble guanylate cyclase stimulator (sGC). Ask your healthcare provider if you are not sure if you are taking an sGC medicine.
  • are pregnant. See Important information.

Before taking Verquvo

Before you start treatment, tell your healthcare provider about all your medical conditions, including if you:

  • are breastfeeding or plan to breastfeed. It is not known if Verquvo passes into your breast milk. Do not breastfeed if you take Verquvo. Talk with your healthcare provider about the best way to feed your baby if you take Verquvo.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Certain other medicines may affect how Verquvo works.

How should I take Verquvo?

  • Take Verquvo exactly as your healthcare provider tells you to.
  • Take Verquvo tablets 1 time each day with food.
  • Swallow the tablets whole. If you are not able to swallow the tablet whole, you may crush the tablet and mix with water right before taking your dose.
  • Your healthcare provider may change your dose -- when you first start taking Verquvo to find the best dose for you and how well you tolerate Verquvo.
  • If you miss a dose, take the missed dose as soon as you remember on the same day of the missed dose. Do not take 2 doses on the same day to make up for a missed dose.
  • If you take too much Verquvo, call your healthcare provider or go to the nearest hospital emergency room right away.

Verquvo side effects

Verquvo may cause serious side effects, including:

  • See Important information

The most common side effects include:

  • low blood pressure
  • low red blood cells (anemia)

These are not all the possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA 1088.

How should I store Verquvo?

  • Store Verquvo at room temperature between 68°F to 77°F (20°C to 25°C).
  • Keep all medicines out of the reach of children and pets.

General information about the safe and effective use of Verquvo.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use this medicine for a condition for which it was not prescribed. Do not give it to other people, even if they have the same symptoms you have. It may harm them.

You can ask your pharmacist or healthcare provider for information that is written for health professionals.

What are the ingredients in Verquvo?

Active ingredient: vericiguat.
Inactive ingredients: croscarmellose sodium, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate.
The tablet film coating contains: hypromellose, talc, titanium dioxide. The film-coating for the 5 mg tablet also contains ferric oxide red. The film-coating for the 10 mg tablet also contains ferric oxide yellow.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.