Silphen DM Drug Interactions
Currently displaying a list of 371 drugs known to interact with Silphen DM (dextromethorphan).
- 78 major drug interactions
- 292 moderate drug interactions
- 1 minor drug interaction
Medications known to interact with Silphen DM
Note: Showing generic names only.
5
A
- abametapir topical
- abiraterone
- acetylcarbromal
- acrivastine
- adagrasib
- adalimumab
- alefacept
- alfentanil
- allopurinol
- almotriptan
- alprazolam
- amiodarone
- amisulpride
- amitriptyline
- amobarbital
- amoxapine
- amphetamine
- anakinra
- apomorphine
- apraclonidine ophthalmic
- aripiprazole
- asenapine
- atomoxetine
- azatadine
- azelastine nasal
B
- baclofen
- benzphetamine
- benztropine
- berotralstat
- bimekizumab
- biperiden
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- brodalumab
- bromocriptine
- brompheniramine
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- canakinumab
- cannabidiol
- cannabis
- capivasertib
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- celecoxib
- cenobamate
- chlophedianol
- chloral hydrate
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorzoxazone
- cimetidine
- cinacalcet
- citalopram
- clemastine
- clobazam
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- cobicistat
- codeine
- cyclizine
- cyclobenzaprine
- cyproheptadine
D
- dacomitinib
- danicopan
- dantrolene
- daridorexant
- darifenacin
- delavirdine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexchlorpheniramine
- dexfenfluramine
- dexmedetomidine
- dextroamphetamine
- dezocine
- diazepam
- difelikefalin
- dihydroergotamine
- dimenhydrinate
- diphenhydramine
- divalproex sodium
- dolasetron
- doxepin
- doxepin topical
- doxylamine
- dronabinol
- dronedarone
- droperidol
- duloxetine
E
- elacestrant
- eletriptan
- eliglustat
- emapalumab
- entacapone
- epcoritamab
- ergotamine
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- eszopiclone
- ethanol
- ethchlorvynol
- ethosuximide
- ethotoin
- ezogabine
F
- fedratinib
- felbamate
- fenfluramine
- fentanyl
- flavoxate
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fosphenytoin
- fostamatinib
- frovatriptan
- furazolidone
G
- gabapentin
- gabapentin enacarbil
- ganaxolone
- gepirone
- givosiran
- glofitamab
- glycerol phenylbutyrate
- golimumab
- granisetron
- guanfacine
- guselkumab
H
I
K
L
- lamotrigine
- lasmiditan
- lemborexant
- lenacapavir
- levetiracetam
- levodopa
- levomethadyl acetate
- levomilnacipran
- levorphanol
- lidocaine
- linezolid
- lisdexamfetamine
- lithium
- lofexidine
- lonapegsomatropin
- lorazepam
- lorcaserin
- loxapine
- lumateperone
- lurasidone
M
- maprotiline
- maribavir
- mavorixafor
- mazindol
- meclizine
- melatonin
- memantine
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methamphetamine
- methdilazine
- methocarbamol
- methohexital
- methotrimeprazine
- methsuximide
- methyldopa
- methylene blue
- metoclopramide
- metyrosine
- mibefradil
- midazolam
- milnacipran
- mirabegron
- mirtazapine
- mitotane
- molindone
- morphine
- morphine liposomal
N
O
- olanzapine
- oliceridine
- olutasidenib
- omaveloxolone
- ondansetron
- opicapone
- opium
- oritavancin
- orphenadrine
- osilodrostat
- oxamniquine
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
- ozanimod
P
- paliperidone
- palonosetron
- panobinostat
- paraldehyde
- paramethadione
- paroxetine
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- phenacemide
- phenelzine
- phenindamine
- phenobarbital
- phensuximide
- phentermine
- phenytoin
- pimozide
- pirtobrutinib
- pralsetinib
- pramipexole
- pregabalin
- pretomanid
- primidone
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propafenone
- propiomazine
- propoxyphene
- protriptyline
- pyrilamine
Q
R
- ramelteon
- ranolazine
- rasagiline
- remifentanil
- remimazolam
- rilonacept
- risperidone
- ritonavir
- rizatriptan
- rolapitant
- ropeginterferon alfa-2b
- ropinirole
- rotigotine
- rufinamide
S
- safinamide
- sarilumab
- satralizumab
- scopolamine
- secobarbital
- secukinumab
- selegiline
- sertraline
- sibutramine
- siltuximab
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- st. john's wort
- stiripentol
- sufentanil
- sumatriptan
- suvorexant
T
- tapentadol
- tarlatamab
- tasimelteon
- tebentafusp
- teclistamab
- tedizolid
- temazepam
- terbinafine
- tetrabenazine
- thalidomide
- thiethylperazine
- thiopental
- thioridazine
- thiothixene
- tiagabine
- ticlopidine
- tizanidine
- tocilizumab
- tolcapone
- tolterodine
- topiramate
- tramadol
- tranylcypromine
- trazodone
- triazolam
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- troglitazone
- tryptophan
U
V
- valbenazine
- valdecoxib
- valerian
- valproic acid
- vemurafenib
- venlafaxine
- vigabatrin
- vilazodone
- viloxazine
- vimseltinib
- vortioxetine
Z
Silphen DM alcohol/food interactions
There is 1 alcohol/food interaction with Silphen DM (dextromethorphan).
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More about Silphen DM (dextromethorphan)
- Silphen DM consumer information
- Check interactions
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: antitussives
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.