Drug Interactions between Aleve and Monodox
This report displays the potential drug interactions for the following 2 drugs:
- Aleve (naproxen)
- Monodox (doxycycline)
Interactions between your drugs
No interactions were found between Aleve and Monodox. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Aleve
A total of 459 drugs are known to interact with Aleve.
- Aleve is in the drug class Nonsteroidal anti-inflammatory drugs.
-
Aleve is used to treat the following conditions:
- Ankylosing Spondylitis
- Aseptic Necrosis (off-label)
- Back Pain
- Bursitis
- Chronic Myofascial Pain
- Costochondritis
- Diffuse Idiopathic Skeletal Hyperostosis
- Dysautonomia
- Fever
- Frozen Shoulder
- Gout, Acute
- Headache
- Muscle Pain
- Neck Pain
- Osteoarthritis
- Pain
- Period Pain
- Rheumatoid Arthritis
- Sciatica
- Spondylolisthesis
- Tendonitis
Monodox
A total of 237 drugs are known to interact with Monodox.
- Monodox is in the following drug classes: miscellaneous antimalarials, tetracyclines.
-
Monodox is used to treat the following conditions:
- Acne
- Actinomycosis
- Amebiasis
- Anthrax
- Anthrax Prophylaxis
- Bacterial Infection
- Bartonellosis
- Bronchitis
- Brucellosis
- Bullous Pemphigoid
- Cervicitis
- Chancroid
- Chlamydia Infection
- Cholera
- Cutaneous Bacillus anthracis
- Ehrlichiosis
- Enterocolitis
- Epididymitis, Sexually Transmitted
- Gastroenteritis
- Gonococcal Infection, Uncomplicated
- Granuloma Inguinale
- Lyme Disease
- Lyme Disease, Arthritis
- Lyme Disease, Carditis
- Lyme Disease, Erythema Chronicum Migrans
- Lyme Disease, Neurologic
- Lymphogranuloma Venereum
- Malaria
- Malaria Prevention
- Melioidosis
- Mycoplasma Pneumonia
- Nongonococcal Urethritis
- Ocular Rosacea
- Pelvic Inflammatory Disease
- Pemphigoid
- Pemphigus
- Periodontitis
- Plague
- Pleural Effusion
- Pneumonia
- Proctitis
- Prostatitis
- Psittacosis
- Rabbit Fever
- Rickettsial Infection
- Rosacea
- Skin or Soft Tissue Infection
- STD Prophylaxis
- Syphilis, Early
- Syphilis, Latent
- Tertiary Syphilis
- Trachoma
- Upper Respiratory Tract Infection
- Urinary Tract Infection
Drug and food/lifestyle interactions
naproxen food/lifestyle
Applies to: Aleve (naproxen)
Ask your doctor before using naproxen together with ethanol (alcohol). Do not drink alcohol while taking naproxen. Alcohol can increase your risk of stomach bleeding caused by naproxen. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
doxycycline food/lifestyle
Applies to: Monodox (doxycycline)
Consumer information for this interaction is not currently available.
GENERALLY AVOID: The oral bioavailability of quinolone and tetracycline antibiotics may be reduced by concurrent administration of preparations containing polyvalent cations such as aluminum, calcium, iron, magnesium, and zinc. Therapeutic failure may result. The proposed mechanism is chelation of quinolone and tetracycline antibiotics by di- and trivalent cations, forming an insoluble complex that is poorly absorbed from the gastrointestinal tract. Reduced gastrointestinal absorption of the cations should also be considered.
MANAGEMENT: Concomitant administration of oral quinolone and tetracycline antibiotics with preparations containing aluminum, calcium, iron, magnesium, and/or zinc salts should generally be avoided. Otherwise, the times of administration should be staggered by as much as possible to minimize the potential for interaction. Quinolones should typically be dosed either 2 to 4 hours before or 4 to 6 hours after polyvalent cation preparations, depending on the quinolone and formulation. Likewise, tetracyclines and polyvalent cation preparations should typically be administered 2 to 4 hours apart. The prescribing information for the antibiotic should be consulted for more specific dosing recommendations.
naproxen food/lifestyle
Applies to: Aleve (naproxen)
Consumer information for this interaction is not currently available.
MONITOR: Smoking cessation may lead to elevated plasma concentrations and enhanced pharmacologic effects of drugs that are substrates of CYP450 1A2 (and possibly CYP450 1A1) and/or certain drugs with a narrow therapeutic index (e.g., flecainide, pentazocine). One proposed mechanism is related to the loss of CYP450 1A2 and 1A1 induction by polycyclic aromatic hydrocarbons in tobacco smoke; when smoking cessation agents are initiated and smoking stops, the metabolism of certain drugs may decrease leading to increased plasma concentrations. The mechanism by which smoking cessation affects narrow therapeutic index drugs that are not known substrates of CYP450 1A2 or 1A1 is unknown. The clinical significance of this interaction is unknown as clinical data are lacking.
MANAGEMENT: Until more information is available, caution is advisable if smoking cessation agents are used concomitantly with drugs that are substrates of CYP450 1A2 or 1A1 and/or those with a narrow therapeutic range. Patients receiving smoking cessation agents may require periodic dose adjustments and closer clinical and laboratory monitoring of medications that are substrates of CYP450 1A2 or 1A1.
doxycycline food/lifestyle
Applies to: Monodox (doxycycline)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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