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Desloratadine / Pseudoephedrine Dosage

Medically reviewed by Drugs.com. Last updated on Jan 31, 2022.

Applies to the following strengths: 5 mg-240 mg; 2.5 mg-120 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Allergic Rhinitis

2.5 mg desloratadine / 120 mg pseudoephedrine tablets: 1 tablet orally every 12 hours
Maximum dose: 1 tablet twice daily

Comments:

  • Higher doses or more frequent dosing has not shown increased effectiveness, but may have more adverse effects.

Use: Relief of seasonal allergic rhinitis symptoms

Usual Pediatric Dose for Allergic Rhinitis

12 and older:
2.5 mg desloratadine / 120 mg pseudoephedrine tablets: 1 tablet orally every 12 hours
Maximum dose: 1 tablet twice daily

Comments:

  • Higher doses or more frequent dosing has not shown increased effectiveness, but may have more adverse effects.

Use: Relief of seasonal allergic rhinitis symptoms

Renal Dose Adjustments

Not recommended.

  • Renally impaired patients may accumulate pseudoephedrine.

Liver Dose Adjustments

Not recommended.

Precautions

CONTRAINDICATIONS:

  • Hypersensitivity to any of the ingredients
  • Narrow angle glaucoma
  • Urinary retention
  • Current monoamine oxidase inhibitor (MAOI) use or use within 14 days of stopping a MAOI
  • Severe hypertension
  • Severe coronary artery disease

Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

  • Use should be avoided in renal impairment.
  • Renally impaired patients may accumulate pseudoephedrine.

Other Comments

Administration advice:

  • Swallow extended release tablets whole; do not crush, break, or chew.
  • Do not exceed the recommended dosage.
  • May be taken with or without food.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.