Clarinex-D 24 Hour
Generic Name: desloratadine and pseudoephedrine (DES loe RAT a deen and SOO doe ee FED rin)
Brand Names: Clarinex-D 24 Hour
Medically reviewed by P. Thornton, DipPharm Last updated on Mar 3, 2019.
What is Clarinex-D 24 Hour?
Clarinex-D 24 Hour contains a combination of desloratadine and pseudoephedrine. Desloratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
Clarinex-D 24 Hour is for adults and children who are at least 12 years old.
Do not use Clarinex-D 24 Hour if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.
Before taking this medicine
You should not use Clarinex-D 24 Hour if you are allergic to desloratadine, loratadine (Claritin), or pseudoephedrine, or if you have:
severe coronary artery disease (clogged arteries);
uncontrolled high blood pressure; or
bladder obstruction or other urination problems.
Do not use Clarinex-D 24 Hour if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Tell your doctor if you have ever had:
heart disease or high blood pressure;
a seizure (in you or a family member);
thyroid disorder; or
Clarinex-D 24 Hour should not be given to a child younger than 12 years old.
It is not known whether desloratadine and pseudoephedrine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breast feed while using Clarinex-D 24 Hour.
How should I take Clarinex-D 24 Hour?
Take Clarinex-D 24 Hour exactly as directed on the label, or as prescribed by your doctor. Cold or allergy medicine is only for short-term use until your symptoms clear up.
Swallow the tablet whole and do not crush, chew, or break it.
Call your doctor if your symptoms do not improve after 7 days, or if you have a fever.
Store at room temperature away from moisture and heat.
Clarinex-D 24 Hour dosing information
Usual Adult Dose for Allergic Rhinitis:
desloratadine-pseudoephedrine 5 mg-240 mg oral tablet, extended release:
one extended release tablet orally once daily
Usual Pediatric Dose for Allergic Rhinitis:desloratadine-pseudoephedrine 5 mg-240 mg oral tablet, extended release:
one extended release tablet orally once daily
What happens if I miss a dose?
Since Clarinex-D 24 Hour is used when needed, you may not be on a daily dosing schedule. If you are on a schedule, take the medicine as soon as you can but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose may cause anxiety, trouble sleeping, headache, vomiting, thirst, muscle weakness, fast or pounding heartbeats, hallucinations, shallow breathing, or a seizure.
What should I avoid while taking Clarinex-D 24 Hour?
This medicine may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how Clarinex-D 24 Hour will affect you.
Drinking alcohol with desloratadine and pseudoephedrine can cause side effects.
Ask a doctor or pharmacist before using over-the-counter medicines. They may contain ingredients similar to Clarinex-D 24 Hour.
Clarinex-D 24 Hour side effects
Get emergency medical help if you have signs of an allergic reaction to Clarinex-D 24 Hour: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using Clarinex-D 24 Hour and call your doctor at once if you have:
a light-headed feeling, like you might pass out;
a seizure; or
a severe skin reaction - fever, skin redness, small pimples.
Common Clarinex-D 24 Hour side effects may include:
nausea, loss of appetite;
sleep problems (insomnia); or
dry mouth, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Clarinex-D 24 Hour?
Using Clarinex-D 24 Hour with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety, depression, or seizures.
Ask a doctor or pharmacist before using desloratadine and pseudoephedrine with any other medications, especially:
any other cold or allergy medicine;
an antibiotic - azithromycin (Zithromax, Z-Pak), erythromycin; or
heart or blood pressure medication - digoxin, digitalis, methyldopa.
This list is not complete. Other drugs may interact with desloratadine and pseudoephedrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2019 Cerner Multum, Inc. Version: 5.01.
More about Clarinex-D 24 Hour (desloratadine / pseudoephedrine)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- En Español
- Drug class: upper respiratory combinations
- FDA Approval History