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Cefzil Dosage

Generic name: cefprozil
Dosage form: tablets, oral suspension
Drug class: Second generation cephalosporins

Medically reviewed by Drugs.com. Last updated on Sep 6, 2021.

CEFZIL is administered orally.

aIn the treatment of infections due to Streptococcus pyogenes, CEFZIL should be administered for at least 10 days.
bNot to exceed recommended adult doses.
Population/Infection Dosage
(mg)		 Duration
(days)
ADULTS (13 years and older)
UPPER RESPIRATORY TRACT
Pharyngitis/Tonsillitis 500 q24h 10a
Acute Sinusitis
(For moderate to severe infections, the higher dose
should be used)		 250 q12h or
500 q12h		 10
LOWER RESPIRATORY TRACT
Secondary Bacterial Infection of Acute Bronchitis and
Acute Bacterial Exacerbation of Chronic Bronchitis		 500 q12h 10
SKIN AND SKIN STRUCTURE
Uncomplicated Skin and Skin Structure Infections 250 q12h or
500 q24h or
500 q12h		 10
CHILDREN (2 years–12 years)
UPPER RESPIRATORY TRACTb
Pharyngitis/Tonsillitis 7.5 mg/kg q12h 10a
SKIN AND SKIN STRUCTUREb
Uncomplicated Skin and Skin Structure Infections 20 mg/kg q24h 10
INFANTS & CHILDREN (6 months–12 years)
UPPER RESPIRATORY TRACTb
Otitis Media
(See INDICATIONS AND USAGE and
CLINICAL STUDIES)		 15 mg/kg q12h 10
Acute Sinusitis
(For moderate to severe infections, the higher dose
should be used)		 7.5 mg/kg q12h or
15 mg/kg q12h		 10

Renal Impairment

Cefprozil may be administered to patients with impaired renal function. The following dosage schedule should be used.

*Cefprozil is in part removed by hemodialysis; therefore, cefprozil should be administered after the completion of hemodialysis.
Creatinine Clearance
(mL/min)		 Dosage
(mg)		 Dosing Interval
30–120 standard standard
0–29* 50% of standard standard

Hepatic Impairment

No dosage adjustment is necessary for patients with impaired hepatic function.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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