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Enablex (darifenacin) Disease Interactions

There are 3 disease interactions with Enablex (darifenacin):

Major

Darifenacin (Includes Enablex) ↔ gastric retention

Severe Potential Hazard, Moderate plausibility. Applies to: Gastrointestinal Obstruction, Ulcerative Colitis, Myasthenia Gravis, Constipation

Darifenacin is contraindicated in patients with gastric retention. Darifenacin, like other anticholinergic drugs, may decrease gastrointestinal motility and should be used with caution in patients with gastrointestinal obstructive disorders and conditions such as severe constipation, ulcerative colitis, and myasthenia gravis because of the risk of gastric retention.

Major

Darifenacin (Includes Enablex) ↔ glaucoma

Severe Potential Hazard, Moderate plausibility. Applies to: Glaucoma (Narrow Angle)

Darifenacin is contraindicated in patients with uncontrolled narrow-angle glaucoma. It is recommended to use darifenacin with caution in patients being treated for narrow-angle glaucoma and only where the potential benefits outweigh the risks.

Major

Darifenacin (Includes Enablex) ↔ urinary retention

Severe Potential Hazard, Moderate plausibility. Applies to: Urinary Retention

Darifenacin is contraindicated in patients with urinary retention. Darifenacin is a competitive muscarinic receptor antagonist. It is recommended to use darifenacin with caution in patients with clinically significant bladder outflow obstruction because of the risk of urinary retention.

Enablex (darifenacin) drug interactions

There are 788 drug interactions with Enablex (darifenacin)

Enablex (darifenacin) alcohol/food interactions

There is 1 alcohol/food interaction with Enablex (darifenacin)

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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