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Tessalon Perles Disease Interactions

There is 1 disease interaction with Tessalon Perles (benzonatate).


Antitussives (applies to Tessalon Perles) psychiatric conditions

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Depression, Psychosis, Parkinsonism

Caution should be used when prescribing antitussives such as benzonatate in patients with psychiatric or emotional conditions. Isolated instances of bizarre behavior, including mental confusion and visual hallucinations have been reported in patients taking antitussives, especially when combined with other prescribed drugs such as monoamine oxidase inhibitors.


  1. (2001) "Product Information. Tessalon (benzonatate)." Forest Pharmaceuticals

Tessalon Perles drug interactions

There is 1 drug interaction with Tessalon Perles (benzonatate).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.