Xenical Alternatives Compared
| Xenical (orlistat) | Wegovy (semaglutide) | Semaglutide |
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| Xenical (orlistat) | Wegovy (semaglutide) | Semaglutide |
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Prescription only
Prescribed for Weight Loss (Obesity/Overweight). Xenical may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Cardiovascular Risk Reduction. Wegovy may also be used for purposes not listed in this medication guide. |
Prescription only
Semaglutide lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is taken... View more |
Related suggestions Weight Loss (Obesity/Overweight)
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| More about Xenical (orlistat) | More about Wegovy (semaglutide) | More about Semaglutide | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Xenical has an average rating of 8.4 out of 10 from a total of 123 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 7% reported a negative effect. |
Wegovy has an average rating of 7.4 out of 10 from a total of 411 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 17% reported a negative effect. |
Semaglutide has an average rating of 6.8 out of 10 from a total of 2327 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all Xenical prices |
View all Wegovy prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms Available | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Other orlistat brands include: Alli | Other semaglutide brands include: Ozempic, Rybelsus | Ozempic, Rybelsus, Wegovy | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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13.5 hours |
168 hours |
168 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 145 drugs are known to interact with Xenical:
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A total of 266 drugs are known to interact with Wegovy:
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A total of 266 drugs are known to interact with Semaglutide:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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April 23, 1999 |
N/A |
December 05, 2017 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.