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Xadago Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Xadago Carbidopa / levodopa Sinemet
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Xadago (safinamide) Carbidopa / levodopa Sinemet (carbidopa / levodopa)
Prescription only

Prescribed for Parkinson's Disease. Xadago may also be used for purposes not listed in this medication guide.

Prescription only

Carbidopa/levodopa is a medication that may be used for the treatment of Parkinson's disease that is available in three different strengths: carbidopa/levodopa 10/100, carbidopa/levodopa 25/100 and... View more

Prescription only

Sinemet is a medication that may be used for the treatment of Parkinson's disease that is available in three different strengths: Sinemet 25/100, Sinemet 25/250, and Sinemet 10/100. Dyskinesias... View more

Related suggestions
More about Xadago (safinamide) More about Carbidopa / levodopa More about Sinemet (carbidopa / levodopa)
Generic Status

No lower-cost generic available

Lower-cost generic is available

Lower-cost generic is available
Ratings & Reviews

Xadago has an average rating of 10.0 out of 10 from a total of 4 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect.

Carbidopa / levodopa has an average rating of 7.2 out of 10 from a total of 91 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 21% reported a negative effect.

Sinemet has an average rating of 7.8 out of 10 from a total of 30 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 11% reported a negative effect.

View all 4 reviews

View all 91 reviews

View all 30 reviews

Drug Class
Side Effects

Common side effects include:

  • dyskinesia

See also: Xadago side effects in more detail.

See also: carbidopa / levodopa side effects in more detail.

See also: Sinemet side effects in more detail.
Pricing and Coupons * Prices are without insurance
Quantity 30 tablet
Dosage 50 mg
Per Unit* $40.31
Cost* $1,209.38

View all Xadago prices

Quantity 100 each
Dosage 25 mg-100 mg
Per Unit* $0.29 - $0.32
Cost* $28.72 - $32.26

View all carbidopa / levodopa prices

Quantity 100 tablet
Dosage 10 mg-100 mg
Per Unit* $1.35
Cost* $135.40

View all Sinemet prices and generic prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Dosage Form(s) Available
  • Oral tablet
  • Oral tablet
  • Oral tablet, disintegrating
  • Oral tablet, extended release
  • Oral tablet
Brand Names

N/A

 Atamet, Dhivy, Duopa, Parcopa, Rytary, Sinemet Other carbidopa / levodopa brands include: Atamet, Dhivy, Duopa, Parcopa, Rytary
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

30 hours

2.3 hours

2.3 hours
CSA Schedule ** View glossary of terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category

Summary unavailable.

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
Drug Interactions

A total of 476 drugs are known to interact with Xadago:

  • 71 major drug interactions (299 brand and generic names)
  • 404 moderate drug interactions (1706 brand and generic names)
  • 1 minor drug interactions (2 brand and generic names)

A total of 475 drugs are known to interact with carbidopa / levodopa:

  • 11 major drug interactions (26 brand and generic names)
  • 442 moderate drug interactions (3111 brand and generic names)
  • 22 minor drug interactions (138 brand and generic names)

A total of 475 drugs are known to interact with Sinemet:

  • 11 major drug interactions (26 brand and generic names)
  • 442 moderate drug interactions (3111 brand and generic names)
  • 22 minor drug interactions (138 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • While you are taking safinamide, you must not eat or drink certain foods and beverages that are... View more
  • Using safinamide together with alcohol may increase side effects such as dizziness, drowsiness... View more
  • Alcohol can increase the nervous system side effects of levodopa such as dizziness, drowsiness, and... View more
  • Alcohol can increase the nervous system side effects of levodopa such as dizziness, drowsiness, and... View more
Disease Interactions
First Approval Date

March 21, 2017

May 02, 1975

May 02, 1975
WADA Class View World Anti-Doping Agency classifications.

N/A

N/A

N/A
More Information
Patient resources
Professional Resources
Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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