Xadago Dosage
Generic name: SAFINAMIDE MESYLATE 50mg
Dosage form: tablet, film coated
Drug class: Dopaminergic antiparkinsonism agents
Medically reviewed by Drugs.com. Last updated on Oct 10, 2024.
Dosing Information
The recommended starting dosage of XADAGO is 50 mg administered orally once daily (at the same time of day), without regard to meals. After two weeks, the dosage may be increased to 100 mg once daily, based on individual need and tolerability.
Daily dosages of XADAGO above 100 mg have not been shown to provide additional benefit, and higher dosages increase the risk for adverse reactions. XADAGO has been shown to be effective only in combination with levodopa/carbidopa .
If a dose is missed, the next dose should be taken at the same time the next day.
XADAGO 100 mg should be tapered by decreasing the dose to 50 mg for one week before stopping .
Dosing in Patients with Hepatic Impairment
In patients with moderate hepatic impairment (Child-Pugh B: 7-9), the maximum recommended dosage of XADAGO is 50 mg orally once daily. XADAGO is contraindicated in patients with severe hepatic impairment (Child-Pugh C: 10-15) . If a patient taking 50 mg XADAGO progresses from moderate to severe hepatic impairment, discontinue XADAGO.
Frequently asked questions
More about Xadago (safinamide)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (4)
- Drug images
- Side effects
- During pregnancy
- Generic availability
- FDA approval history
- Drug class: dopaminergic antiparkinsonism agents
- Breastfeeding
- En español
Patient resources
Professional resources
Related treatment guides
See also:
Sinemet
Sinemet is used to treat symptoms of Parkinson's disease, such as muscle stiffness, tremors ...
Cogentin
Cogentin is used for extrapyramidal reaction, parkinson's disease
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Exelon
Exelon (rivastigmine) is used to treat dementia caused by Alzheimer's or Parkinson's disease ...
Gocovri
Gocovri (amantadine) is used in the treatment of Parkinson's disease. Includes Gocovri side ...
Rivastigmine
Rivastigmine systemic is used for alzheimer's disease, lewy body dementia, parkinson's disease
Amantadine
Easy-to-read patient leaflet for amantadine. Includes indications, proper use, special ...
Carbidopa/levodopa
Carbidopa/levodopa systemic is used for GTP-CH Deficiency, neuroleptic malignant syndrome ...
Pramipexole
Pramipexole systemic is used for parkinson's disease, periodic limb movement disorder, restless ...
Benztropine
Benztropine systemic is used for extrapyramidal reaction, hyperhidrosis, parkinson's disease
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.