Carbidopa / levodopa and Depression: What Users Say

• Gig...
• Taken for less than 1 month
• January 2, 2020

Carbidopa / levodopa for Parkinson's Disease "I never took illegal drugs, but my experience was like I heard when people took LSD. I had horrid hallucinatory dreams, sweating, depression, increased anger, lack of impulsive control, weight gain, all within two weeks. Having Parkinson's is better than the side effects I had with this drug."

• You...
• Taken for 2 to 5 years
• November 13, 2017

Carbidopa / levodopa for Parkinson's Disease "I've been on Rytary since 2015 and at times was on 5 pills 4 times a day of the 48.75-195 dosage. Partial neuroleptic seizures were a result, mild psychosis, paranoia, anxiety, mood swings, depression, dyskinesia, dystonia, impulse control, sleeplessness, among others, all things I've dealt with at some point along the way. I'm now on 3 pills 5 times a day, with a small dose of 2 mg Artane in between 4 times a day. I have not been able to really lock down whatever makes it work. It is wildly inconsistent, but when it's on, it's on, and I get some normal time. Certain strains of medical marijuana help increase the efficacy of this drug, kicking in sooner and can give me up to 6-7 hours of normal time instead of 1 hour to kick in and 1-2 hours normal time."

• Hor...
• Taken for 1 to 6 months
• March 1, 2023

For Parkinson's Disease "My husband was on carbidopa/levodopa for about 3 months. Last month, he experienced anger, depression, and much confusion. This has set him back. He was taken off this medication, and I am unsure if he will get back to where he was before starting this medication—terrible experience."

• Ano...
• Taken for 1 to 6 months
• April 29, 2018

Carbidopa / levodopa for Parkinson's Disease "I took Sinemet for about a month, and while it lessened my uncoordinated hand movement, I fell into a very deep depression and was having panic attacks. As soon as I stopped taking it, I was better."

• Anonymous
• February 15, 2018

For Parkinson's Disease "Do not take this if you have a history of depression. My brother was on for 4 days and became more depressed and suicidal. He is only 55 and never has been suicidal in the past."