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Carbidopa / levodopa and Stiffness: What Users Say

Brand names: Sinemet, Rytary, Crexont, Duopa, Parcopa, Dhivy Atamet

Stiffness: mentioned by 4 users (4.3%)

Based on user experiences from 94 Carbidopa / levodopa reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

muscle spasms 12.8%
hallucinations 6.4%
nausea 6.4%
anxiety 5.3%
depression 5.3%
tremors 5.3%
anger 4.3%
drowsiness 4.3%
stiffness 4.3%
confusion 3.2%

Reviews for Carbidopa / levodopa

  • Ban...
  • Taken for less than 1 month
  • March 12, 2015

Carbidopa / levodopa for Parkinson's Disease "I have been taking Rytary for the last 9 days, and it worked great at night since I was sleeping. But it worked about 30%-40% for me as soon as I put something in my mouth. I had a small apple yesterday and took my pills 2 1/2 hours later, and I was stiff, with almost no movement for the next 2 hours. Today I had a very light veggie lunch at noon, took Rytary at 3 pm which worked about 30%, and I finally decided to take my Parcopa at 6 pm on top of Rytary! I would vote for Rytary at night only."

3 / 10
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79 Report
  • Tom...
  • Taken for less than 1 month
  • August 3, 2017

For Restless Legs Syndrome "RLS is horrible. My legs were jumping like an acrobat. Sometimes, during the day, my legs would give out. My neurologist prescribed 25/100 - 3X per day. It was a miracle drug. Stopped RLS immediately. But I had other problems. My body hurt all over and was stiff. My muscles were weak. My legs were heavy, and it was hard to walk. However, the 25/100 fixed it all. I feel great! I have more energy and am getting stronger every day. Cutting down on pain meds, and at 68, I have a wonderful and new quality of life. I've only been taking it for 2 weeks, and I am so thankful. I now sleep 100 percent better. The dose only works around 7-8 hours. I take it every 8 hours. I take it at 8:00 pm, and I wake up around 3-4:00 am with symptoms starting again. It takes 30 minutes to work."

10 / 10
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39 Report
  • Tom...
  • Taken for 1 to 2 years
  • April 28, 2022

Carbidopa / levodopa for Parkinson's Disease "I was taking Rytary 3 capsules 3 times a day of the 95-23 mg, and I didn't realize how good this drug works until I could not afford it anymore. Being on disability, I depended on grants to pay for this drug, but I guess it's the sign of the times that there is no funding available anywhere, and it's back to generic carbidopa/levodopa and being stiff all day. So if you can afford this drug, I highly recommend it. It worked wonderfully for me when I was lucky enough to get it."

10 / 10
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10 Report

Frequently asked questions

  • Jo ...
  • Taken for 1 to 2 years
  • November 22, 2019

For Parkinson's Disease "I have been taking Sinemet for nearly two years. I do not have a tremor. The drug helps relieve muscle stiffness and pain and helps my balance somewhat. However, it does nothing to help my slow movements and weakness, my speech, insomnia, etc."

6 / 10
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7 Report

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