Saphnelo Alternatives Compared
| Saphnelo | Plaquenil | Hydroxychloroquine |
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| Saphnelo (anifrolumab) | Plaquenil (hydroxychloroquine) | Hydroxychloroquine |
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Prescription only
Prescribed for Systemic Lupus Erythematosus. Saphnelo may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Lyme Disease - Arthritis, Rheumatoid Arthritis, Dermatomyositis, Systemic Lupus Erythematosus, Malaria, Malaria Prevention. Plaquenil may also be used for purposes not listed in this... View more |
Prescription only
Prescribed for Lyme Disease - Arthritis, Rheumatoid Arthritis, Dermatomyositis, Systemic Lupus Erythematosus, Malaria, Malaria Prevention. May also be prescribed off label for Lichen Planopilaris... View more |
Related suggestions Systemic Lupus Erythematosus
Popular comparisons
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| More about Saphnelo (anifrolumab) | More about Plaquenil (hydroxychloroquine) | More about Hydroxychloroquine | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Saphnelo has an average rating of 5.0 out of 10 from a total of 1 ratings on Drugs.com. 0% of reviewers reported a positive effect, while 0% reported a negative effect. |
Plaquenil has an average rating of 6.5 out of 10 from a total of 158 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 26% reported a negative effect. |
Hydroxychloroquine has an average rating of 6.5 out of 10 from a total of 348 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 28% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: Saphnelo side effects in more detail. |
See also: Plaquenil side effects in more detail. |
See also: hydroxychloroquine side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Saphnelo prices |
View all Plaquenil prices and generic prices |
View all hydroxychloroquine prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
Plaquenil | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 199 drugs are known to interact with Saphnelo:
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A total of 455 drugs are known to interact with Plaquenil:
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A total of 455 drugs are known to interact with hydroxychloroquine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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July 30, 2021 |
April 18, 1955 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.