Comparing Rexulti vs Sertraline
| Rexulti | Sertraline |
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| Rexulti (brexpiprazole) | Sertraline |
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Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression. Most people experience some improvement in their symptoms within 1 to 2 weeks of starting... View more |
Prescription only
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Prescribed for Major Depressive Disorder, Obsessive Compulsive Disorder, Panic Disorder... View more |
Related suggestions Major Depressive Disorder
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| More about Rexulti (brexpiprazole) | More about Sertraline | ||||||||||||||||
| Generic Status | |||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | |||||||||||||||||
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Rexulti has an average rating of 6.4 out of 10 from a total of 399 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 28% reported a negative effect. |
Sertraline has an average rating of 7.2 out of 10 from a total of 4105 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 19% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: Rexulti side effects in more detail. |
Commonly reported side effects include:
See also: sertraline side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Rexulti prices |
View all sertraline prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Zoloft | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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91 hours |
66 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 537 drugs are known to interact with Rexulti:
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A total of 642 drugs are known to interact with sertraline:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 10, 2015 |
December 30, 1991 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.