Comparing Rexulti vs Sertraline
| Rexulti (brexpiprazole) | Sertraline |
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| Rexulti (brexpiprazole) | Sertraline |
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Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Prescription only
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Headaches, nausea, diarrhea, weight loss, insomnia, tremors, and sexual dysfunction are the... View more |
Related suggestions Depression
Major Depressive Disorder
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| More about Rexulti (brexpiprazole) | More about Sertraline | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Rexulti has an average rating of 6.6 out of 10 from a total of 497 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 25% reported a negative effect. |
Sertraline has an average rating of 7.3 out of 10 from a total of 4581 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Rexulti side effects |
View all Sertraline side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Rexulti prices |
View all Sertraline prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Zoloft | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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91 hours |
66 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 601 drugs are known to interact with Rexulti:
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A total of 673 drugs are known to interact with Sertraline:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 10, 2015 |
December 30, 1991 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.