Comparing Rexulti vs Sertraline
Rexulti Remove Rexulti from your drug comparison | Sertraline Remove Sertraline from your drug comparison |
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Rexulti brexpiprazole Remove Rexulti from your drug comparison | Sertraline Remove Sertraline from your drug comparison | ||||||||||||||||
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Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression. Most people experience some improvement in their symptoms within 1 to 2 weeks of starting... View more |
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Prescribed for Panic Disorder, Major Depressive Disorder, Obsessive Compulsive Disorder,... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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6.3
For Major Depressive Disorder: I have been on rexulti for 1 month now. It is totally amazing for treatment resistant depression, I haven't felt this good in about 20 years, but am having massive weight gain issues. Can anyone tell me how to get the weight off, as, not eating or exercise is not helping. Would appreciate some advice..thank you |
7.2
For Anxiety and Stress: I have decided to help myself. Today is my third day of Sertraline at 7am every morning: Weird lump sensation in my throat coupled with sicky feeling in tummy. I've totally lost my appetite by midday, forcing myself to eat. By midday I'm yawning a lot, a pretty tired and achey. By evening I am sleepy and drowsy. The main thing above all that I have noticed is that I feel flat, which is not a bad thing at all. Just days before I went on these meds I was constantly crying, shaking, wanting to my life to be over. I couldn't have a moment to myself without thinking negative thoughts. I had some bad news this morning from my energy provider which would normally send me into melt down, but I handled it with calmness. Very surprised and proud of myself. Bottom line: I'm bracing myself for side effects to worsen, but fingers crossed they don't. Right now they are certainly manageable and I'm glad I didn't let the reviews put me off. For Anxiety and Stress: Started Zoloft 15days ago and have been having a tough time with the up and downs. The past two day’s have been bad with lots of anxiety, and shaking with lots of crying on the floor. The doctors warned me of these symptoms and encouraged me to be strong and that it will get better with time and to trust its the process as it balancing me out. I’m not having suicidal thoughts anymore so that’s a relief. My appetite has surely decreased although it seems that smoking a little marijuana helped me with that but would prefer not to have to smoke to eat. I should feel grateful that I’m actually feeling something again even if it hurts because nothings is as bad as the place I was at — I look forward to happy days again. Stay strong |
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Drug Class |
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Side Effects |
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See the full Rexulti side effects document. |
Commonly reported side effects include: diarrhea, dizziness, drowsiness, dyspepsia, fatigue, insomnia, loose stools, nausea, tremor, headache, paresthesia, anorexia, decreased libido, delayed ejaculation, diaphoresis, ejaculation failure, and xerostomia. See the full sertraline side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Rexulti prices |
View all sertraline prices |
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Generic Availability |
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No |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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N/A |
Zoloft | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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91 hours |
66 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Summary unavailable. See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
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Drug Interactions |
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A total of 512 drugs are known to interact with Rexulti:
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A total of 616 drugs are known to interact with sertraline:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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July 10, 2015 |
December 30, 1991 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Major Depressive Disorder: Rexulti took time to start working and now I feel better than I have for awhile. I've lost my parents and my ESA in the last 6 years. The downside is the weight gain. I've gained 20 lbs in a short period of time. I can't afford to gain weight, I'm already big. I eat the same things, I don't snack. In comparison, before Rexulti I ate more than I do now and didn't gain weight. It's the weight gain that makes it problematic.