Comparing Pristiq vs Savella
| Pristiq (desvenlafaxine) | Savella (milnacipran) |
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| Pristiq (desvenlafaxine) | Savella (milnacipran) |
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Prescription only
Prescribed for Major Depressive Disorder, Depression. Pristiq may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Fibromyalgia. Savella may also be used for purposes not listed in this medication guide. |
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| More about Pristiq (desvenlafaxine) | More about Savella (milnacipran) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Pristiq has an average rating of 6.9 out of 10 from a total of 1127 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 22% reported a negative effect. |
Savella has an average rating of 6.7 out of 10 from a total of 347 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Pristiq side effects |
View all Savella side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Pristiq prices |
View all Savella prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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11 hours |
10 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 481 drugs are known to interact with Pristiq:
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A total of 383 drugs are known to interact with Savella:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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February 29, 2008 |
January 14, 2009 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.