Comparing Phenylephrine vs Zicam Sinus Relief
| Phenylephrine | Zicam Sinus Relief (oxymetazoline) |
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| Phenylephrine | Zicam Sinus Relief (oxymetazoline) |
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Prescription and OTC
Phenylephrine relieves congestion of the nasal passages and is found in many cold and flu remedies. There is some controversy over whether it works at the dosages usually found in over-the-counter... View more |
Over-the-counter
Prescribed for Nasal Congestion. Zicam Sinus Relief may also be used for purposes not listed in this medication guide. |
Related suggestions Nasal Congestion
Popular comparisons
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| More about Phenylephrine | More about Zicam Sinus Relief (oxymetazoline) | ||||||||
| Ratings & Reviews | |||||||||
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Phenylephrine has an average rating of 6.2 out of 10 from a total of 23 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 39% reported a negative effect. |
Zicam Sinus Relief has an average rating of 10.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
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View all Phenylephrine side effects |
View all Zicam Sinus Relief side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Phenylephrine prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| AH-Chew D, Biorphen, Congest Aid II, Contac-D, Despec-SF, Dimetapp Toddler's Drops Decongestant, Gilchew IR, Little Colds Decongestant, Nasal Decongestant PE, Nasop, Nasop12, Neo-Synephrine, Ricobid-D, Sudafed PE Children's Nasal Decongestant, Sudafed PE Congestion, Sudogest PE, Suphedrine PE, Vazculep View more | Other oxymetazoline brands include: 12 Hour Nasal, 12 Hour Nasal Decongestant Spray, Afrin, Afrin Allergy Sinus Nasal Spray, Afrin NoDrip Allergy Sinus, Afrin NoDrip Extra Moisturizing, Afrin NoDrip Original, Afrin NoDrip Severe Congestion, Afrin NoDrip Sinus, Afrin Original, Afrin Severe Congestion, Afrin Sinus, Allerest 12 Hour Nasal Spray, CVS Health Sinus Relief, Dristan 12 Hour Nasal Spray, Duramist Plus, Duration, Four-Way Nasal Spray, Genasal, Giltuss Severe Sinus, Mucinex Sinus-Max Clear & Cool, Mucinex Sinus-Max Full Force, Mucinex Sinus-Max Moisture Smart, Nostrilla, Nostrilla 12 Hour, Rhinase D Moisturizing Nasal Decongestant, Todays Health Nasal Relief Extra Moisturizing, Vicks QlearQuil 12 Hour Nasal Decongestant Moisturizing Spray, Vicks Sinex 12-Hour Decongestant Nasal Spray, Vicks Sinex 12-Hour Decongestant UltraFine Mist, Vicks Sinex Moisturizing 12-Hour Decongestant UltraFine Mist, Vicks Sinex Severe Nasal Spray, Zicam Extreme Congestion Relief View more | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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N/A |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 201 drugs are known to interact with Phenylephrine:
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A total of 51 drugs are known to interact with Zicam Sinus Relief:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 20, 2012 |
N/A |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
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N/A |
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| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.