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Ortho Tri-Cyclen Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Ortho Tri-Cyclen Remove Ortho Tri-Cyclen from your drug comparison Medroxyprogesterone Remove Medroxyprogesterone from your drug comparison Mirena Remove Mirena from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Ortho Tri-Cyclen ethinyl estradiol / norgestimate Remove Ortho Tri-Cyclen from your drug comparison Medroxyprogesterone Remove Medroxyprogesterone from your drug comparison Mirena levonorgestrel Remove Mirena from your drug comparison

Prescribed for Acne, Birth Control, Endometriosis, Abnormal Uterine Bleeding, Gonadotropin Inhibition. May also be prescribed off label for Ovarian Cysts.

Prescribed for Abnormal Uterine Bleeding, Amenorrhea, Birth Control, Endometrial Hyperplasia - Prophylaxis, Endometriosis, Endometrial Cancer. May also be prescribed off label for Gender Dysphoria,... View more

Prescribed for Abnormal Uterine Bleeding, Birth Control. Mirena may also be used for purposes not listed in this medication guide.

Prescription only

Prescription only

Prescription only

Ratings & Reviews

View all 258 reviews

View all 2134 reviews

View all 2340 reviews

Drug Class

Side Effects

See the full Ortho Tri-Cyclen side effects document.

See the full medroxyprogesterone side effects document.

See the full Mirena side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 168 each
Dosage triphasic 35 mcg
Per Unit* $1.91 - $1.92
Cost* $321.32 - $322.32

View all and generic prices

Quantity 5 tablet
Dosage 10 mg
Per Unit* $2.10
Cost* $10.48

View all medroxyprogesterone prices

Quantity 1 device
Dosage 52 mg
Per Unit* $1,052.75
Cost* $1,052.75

View all Mirena prices and generic prices

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Generic Availability

Yes

Yes (this medicine)

Yes

Dosage Form(s) Available
  • Oral tablet
  • Intramuscular suspension
  • Oral tablet
  • Intrauterine device

Brand Names
Other ethinyl estradiol / norgestimate brands include: Estarylla, Femynor, Mili, Mono-Linyah, Nymyo, Previfem, Sprintec, Tri Femynor, Tri-Estarylla, Tri-Linyah, Tri-Lo-Estarylla, Tri-Lo-Marzia, Tri-Lo-Mili, Tri-Lo-Sprintec, Tri-Mili, Tri-Nymyo, Tri-Previfem, Tri-Sprintec, Tri-VyLibra, Tri-Vylibra Lo, VyLibra View more Depo-Provera, depo-subQ provera 104, Provera Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, BionaFem, EContra EZ, EContra One-Step, Fallback Solo, Kyleena, Liletta, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Plan B One-Step, PostDay One-Step, Preventeza, React, Skyla, Take Action View more

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

N/A

401 hours

45 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
X
Category X Not for use in pregnancy

See the full Pregnancy Warnings document.
X
Category X Not for use in pregnancy

See the full Pregnancy Warnings document.
X
Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (1)

FDA Alerts (1)

N/A

Drug Interactions

A total of 412 drugs are known to interact with Ortho Tri-Cyclen:

  • 34 major drug interactions (95 brand and generic names)
  • 333 moderate drug interactions (1197 brand and generic names)
  • 45 minor drug interactions (480 brand and generic names)

A total of 201 drugs are known to interact with medroxyprogesterone:

  • 17 major drug interactions (45 brand and generic names)
  • 177 moderate drug interactions (570 brand and generic names)
  • 7 minor drug interactions (24 brand and generic names)

A total of 214 drugs are known to interact with Mirena:

  • 31 major drug interactions (87 brand and generic names)
  • 171 moderate drug interactions (543 brand and generic names)
  • 12 minor drug interactions (33 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • Grapefruit juice may increase the blood levels of certain medications such as norgestimate. You... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
  • Grapefruit juice may increase the blood levels of certain medications such as levonorgestrel. You... View more

Disease Interactions

First Approval Date

July 03, 1992

June 18, 1959

December 06, 2000

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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