Comparing Ortho Tri-Cyclen vs Ortho Tri-Cyclen Lo

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Ortho Tri-Cyclen (ethinyl estradiol / norgestimate)	Ortho Tri-Cyclen Lo (ethinyl estradiol / norgestimate)	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Ortho Tri-Cyclen (ethinyl estradiol / norgestimate)	Ortho Tri-Cyclen Lo (ethinyl estradiol / norgestimate)	Enter another drug to compare
Prescription only Prescribed for Endometriosis, Ovarian Cysts, Acne, Abnormal Uterine Bleeding, Birth Control, Gonadotropin Inhibition. Ortho Tri-Cyclen may also be used for purposes not listed in this medication guide. View more	Prescription only Prescribed for Endometriosis, Ovarian Cysts, Abnormal Uterine Bleeding, Birth Control, Gonadotropin Inhibition. Ortho Tri-Cyclen Lo may also be used for purposes not listed in this medication guide.	Related suggestions Birth Control Mirena Nexplanon Lo Loestrin Fe NuvaRing Depo Provera Sprintec Abnormal Uterine Bleeding Medroxyprogesterone Norethindrone Provera Megestrol Sprintec Premarin Endometriosis Norethindrone Lupron Depot Orilissa Progesterone Medroxyprogesterone Zoladex Ovarian Cysts Sprintec Ethinyl estradiol / levonorgestrel Ethinyl estradiol / norgestimate Tri-Sprintec Levora Estarylla Popular comparisons Ortho Tri-Cyclen vs Yaz
More about Ortho Tri-Cyclen (ethinyl estradiol / norgestimate)	More about Ortho Tri-Cyclen Lo (ethinyl estradiol / norgestimate)
Ratings & Reviews
Ortho Tri-Cyclen has an average rating of 5.7 out of 10 from a total of 266 ratings on Drugs.com. 39% of reviewers reported a positive effect, while 32% reported a negative effect.	Ortho Tri-Cyclen Lo has an average rating of 6.2 out of 10 from a total of 357 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 26% reported a negative effect.
View all 266 reviews	View all 357 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Acne (26.7%) Mood swings (26.3%) Weight gain (23.7%) Depression (19.9%) Nausea (16.9%) Cramps (15.0%) Headaches (10.2%) View all Ortho Tri-Cyclen side effects	Mood swings (28.9%) Weight gain (23.8%) Nausea (22.4%) Acne (19.3%) Cramps (17.9%) Depression (17.1%) Headaches (13.2%) View all Ortho Tri-Cyclen Lo side effects
Drug Class
Contraceptives	Contraceptives
Generic Availability
Lower cost generic approved	Lower cost generic approved
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
Oral tablet	Oral tablet
Brand Names
Other ethinyl estradiol / norgestimate brands include: Estarylla, Femynor, Mili, Mono-Linyah, Nymyo, Previfem, Sprintec, Tri Femynor, Tri-Estarylla, Tri-Linyah, Tri-Lo-Estarylla, Tri-Lo-Linyah, Tri-Lo-Marzia, Tri-Lo-Mili, Tri-Lo-Sprintec, Tri-Mili, Tri-Nymyo, Tri-Previfem, Tri-Sprintec, Tri-VyLibra, Tri-Vylibra Lo, VyLibra View more	Other ethinyl estradiol / norgestimate brands include: Estarylla, Femynor, Mili, Mono-Linyah, Nymyo, Previfem, Sprintec, Tri Femynor, Tri-Estarylla, Tri-Linyah, Tri-Lo-Estarylla, Tri-Lo-Linyah, Tri-Lo-Marzia, Tri-Lo-Mili, Tri-Lo-Sprintec, Tri-Mili, Tri-Nymyo, Tri-Previfem, Tri-Sprintec, Tri-VyLibra, Tri-Vylibra Lo, VyLibra View more
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
N/A	N/A
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
X Category X Not for use in pregnancy See the full pregnancy warnings document.	X Category X Not for use in pregnancy See the full pregnancy warnings document.
Drug Interactions
A total of 496 drugs are known to interact with Ortho Tri-Cyclen: 75 major drug interactions (195 brand and generic names) 372 moderate drug interactions (1389 brand and generic names) 49 minor drug interactions (527 brand and generic names)	A total of 496 drugs are known to interact with Ortho Tri-Cyclen Lo: 75 major drug interactions (195 brand and generic names) 372 moderate drug interactions (1389 brand and generic names) 49 minor drug interactions (527 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Grapefruit juice may increase the blood levels of certain medications such as norgestimate. You... View more	Grapefruit juice may increase the blood levels of certain medications such as norgestimate. You... View more
Disease Interactions
Smoking Abnormal vaginal bleeding Carcinomas (estrogenic) Hypercalcemia in breast cancer Hypertension Thromboembolism/cardiovascular Hepatic neoplasms Liver disease Thromboembolism Angioedema Gallbladder disease Hypercalcemia Hyperlipidemia Liver disease Melasma Depression Fluid retention Glucose intolerance Retinal thrombosis Thyroid function tests Hyperlipidemia Weight gain	Smoking Abnormal vaginal bleeding Carcinomas (estrogenic) Hypercalcemia in breast cancer Hypertension Thromboembolism/cardiovascular Hepatic neoplasms Liver disease Thromboembolism Angioedema Gallbladder disease Hypercalcemia Hyperlipidemia Liver disease Melasma Depression Fluid retention Glucose intolerance Retinal thrombosis Thyroid function tests Hyperlipidemia Weight gain
First Approval Date
July 03, 1992	N/A
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pregnancy warnings Drug images Support group	Side effects Drug interactions Dosage Pregnancy warnings Drug images Support group
Patient Resources
Ortho Tri-Cyclen uses	Ortho Tri-Cyclen Lo uses Advanced reading
Professional Resources
Prescribing information	Prescribing information
Related Treatment Guide
Endometriosis Ovarian Cysts Acne Abnormal Uterine Bleeding Birth Control Gonadotropin Inhibition	Endometriosis Ovarian Cysts Abnormal Uterine Bleeding Birth Control Gonadotropin Inhibition

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

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Comparing Ortho Tri-Cyclen vs Ortho Tri-Cyclen Lo

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Comparing Ortho Tri-Cyclen vs Ortho Tri-Cyclen Lo

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