Comparing Norethindrone vs Skyla
| Norethindrone | Skyla |
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| Norethindrone | Skyla (levonorgestrel) |
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Prescription only
Prescribed for Abnormal Uterine Bleeding, Endometriosis, Amenorrhea, Gender Affirming Hormone Therapy , Birth Control. norethindrone may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Birth Control. Skyla may also be used for purposes not listed in this medication guide. |
Related suggestions Birth Control (Contraception)
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| More about Norethindrone | More about Skyla (levonorgestrel) | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Norethindrone has an average rating of 4.8 out of 10 from a total of 1484 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 46% reported a negative effect. |
Skyla has an average rating of 6.9 out of 10 from a total of 1529 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Commonly reported side effects include:
See also: norethindrone side effects in more detail. |
Common side effects include:
See also: Skyla side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all norethindrone prices |
View all Skyla prices and generic prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Camila, Deblitane, Errin, Heather, Incassia, Jencycla, Lyleq, Lyza, Nor-QD, Norlyda, Norlyroc, Sharobel, Tulana View more | Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, BionaFem, EContra EZ, EContra One-Step, Fallback Solo, Kyleena, Liletta, Mirena, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Plan B One-Step, PostDay One-Step, Preventeza, React, Take Action View more | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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10 hours |
45 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 237 drugs are known to interact with norethindrone:
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A total of 231 drugs are known to interact with Skyla:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 21, 1982 |
January 09, 2013 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.