Comparing Norethindrone vs Skyla
| Norethindrone | Skyla (levonorgestrel) |
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| Norethindrone | Skyla (levonorgestrel) |
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Prescription only
Prescribed for Abnormal Uterine Bleeding, Endometriosis, Amenorrhea, Gender Affirming Hormone Therapy, Birth Control. Norethindrone may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Birth Control. Skyla may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Norethindrone | More about Skyla (levonorgestrel) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Norethindrone has an average rating of 4.9 out of 10 from a total of 1573 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 45% reported a negative effect. |
Skyla has an average rating of 6.9 out of 10 from a total of 1537 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 19% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Norethindrone side effects |
View all Skyla side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Norethindrone prices |
View all Skyla prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Affodel, Camila, Deblitane, Emzahh, Errin, Gallifrey, Heather, Incassia, Jencycla, Lyleq, Lyza, Meleya, Nor-QD, Norlyda, Norlyroc, Orquidea, Sharobel, Tulana View more | Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, Curae, EContra One-Step, Fallback Solo, Her Style, Julie, Kyleena, Liletta, Mirena, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Optionelle, Plan B One-Step, PostDay One-Step, SheWise, Take Action View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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10 hours |
45 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 266 drugs are known to interact with Norethindrone:
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A total of 261 drugs are known to interact with Skyla:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 21, 1982 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.