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Skyla Side Effects

Generic name: levonorgestrel

Medically reviewed by Drugs.com. Last updated on Nov 2, 2024.

Note: This document provides detailed information about Skyla Side Effects associated with levonorgestrel. Some dosage forms listed on this page may not apply specifically to the brand name Skyla.

Applies to levonorgestrel: oral tablet.

Other dosage forms:

Serious side effects of Skyla

Along with its needed effects, levonorgestrel (the active ingredient contained in Skyla) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking levonorgestrel:

More common side effects

  • heavy or light menstrual bleeding

Incidence not known

  • absent missed or irregular menstrual periods
  • cramps
  • irregular menstruation
  • pain
  • pain in the pelvis
  • stopping of menstrual bleeding

Other side effects of Skyla

Some side effects of levonorgestrel may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • abdominal or stomach pain
  • dizziness
  • headache
  • nausea
  • tenderness of the breasts
  • unusual tiredness or weakness
  • vomiting

Less common side effects

For healthcare professionals

Applies to levonorgestrel: intrauterine device, oral tablet, subcutaneous implant.

General adverse events

The most commonly reported adverse effects are alterations of menstrual bleeding patterns, nausea, abdominal/pelvic pain, headache/migraine, dizziness, fatigue, amenorrhea, ovarian cysts, genital discharge, acne/seborrhea, breast tenderness, and vulvovaginitis.[Ref]

Genitourinary

Gastrointestinal

Other

Nervous system

Psychiatric

Dermatologic

Cardiovascular

Musculoskeletal

Oncologic

Ocular

Metabolic

Hypersensitivity

References

1. (2003) "Product Information. Mirena (levonorgestrel)." Berlex Laboratories

2. (2003) "Product Information. Plan B (levonorgestrel)." Women's Capital Corporation

3. Cerner Multum, Inc. "UK Summary of Product Characteristics."

4. Cerner Multum, Inc. "Australian Product Information."

5. (2013) "Product Information. Skyla (levonorgestrel)." Bayer Pharmaceutical Inc

6. (2016) "Product Information. Liletta (levonorgestrel)." Actavis Pharma, Inc.

7. (2018) "Product Information. Kyleena (levonorgestrel)." Bayer Pharmaceutical Inc

Frequently asked questions

Further information

Skyla side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.