Comparing Nitrofurantoin vs Trimethoprim
Nitrofurantoin | Trimethoprim |
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Nitrofurantoin | Trimethoprim |
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Prescription only
Nitrofurantoin is an effective antibiotic with a low risk of inducing bacterial resistance that is used specifically to treat urinary tract infections caused by susceptible bacteria. Long-term use... View more |
Prescription only
Prescribed for Urinary Tract Infection, Prevention of Bladder infection, Bladder Infection, Pneumocystis Pneumonia, Middle Ear Infections. Trimethoprim may also be used for purposes not listed in... View more |
Related suggestions Urinary Tract Infection
Bladder Infection
Prevention of Bladder infection (Cystitis Prophylaxis)
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More about Nitrofurantoin | More about Trimethoprim | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Nitrofurantoin has an average rating of 4.5 out of 10 from a total of 1891 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 52% reported a negative effect. |
Trimethoprim has an average rating of 3.1 out of 10 from a total of 196 ratings on Drugs.com. 13% of reviewers reported a positive effect, while 70% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Nitrofurantoin side effects |
View all Trimethoprim side effects |
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Drug Class | |||||||||||||||||
Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Nitrofurantoin prices |
View all Trimethoprim prices |
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Dosage Forms | |||||||||||||||||
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Brand Names | |||||||||||||||||
Furadantin, Macrobid, Macrodantin | Primsol | ||||||||||||||||
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
1 hour |
14 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 224 drugs are known to interact with Nitrofurantoin:
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A total of 163 drugs are known to interact with Trimethoprim:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
February 06, 1953 |
May 30, 1980 |
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WADA Class View classifications | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient Resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.