Myfembree Alternatives Compared
| Myfembree | Norethindrone | Orilissa |
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| Myfembree (estradiol / norethindrone / relugolix) | Norethindrone | Orilissa (elagolix) |
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Prescription only
Prescribed for Endometriosis, Uterine Fibroids. Myfembree may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Abnormal Uterine Bleeding, Endometriosis, Amenorrhea, Gender Affirming Hormone Therapy , Birth Control. norethindrone may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Endometriosis. Orilissa may also be used for purposes not listed in this medication guide. |
Related suggestions Endometriosis
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| More about Myfembree (estradiol / norethindrone / relugolix) | More about Norethindrone | More about Orilissa (elagolix) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Myfembree has an average rating of 6.8 out of 10 from a total of 4 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 25% reported a negative effect. |
Norethindrone has an average rating of 4.9 out of 10 from a total of 1551 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 45% reported a negative effect. |
Orilissa has an average rating of 5.3 out of 10 from a total of 126 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 40% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: Myfembree side effects in more detail. |
See also: norethindrone side effects in more detail. |
See also: Orilissa side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Myfembree prices |
View all norethindrone prices |
View all Orilissa prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Affodel, Camila, Deblitane, Emzahh, Errin, Heather, Incassia, Jencycla, Lyleq, Lyza, Nor-QD, Norlyda, Norlyroc, Sharobel, Tulana View more |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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60.8 hours |
10 hours |
6 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 605 drugs are known to interact with Myfembree:
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A total of 247 drugs are known to interact with norethindrone:
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A total of 349 drugs are known to interact with Orilissa:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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May 26, 2021 |
April 21, 1982 |
July 23, 2018 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.