Comparing Mirtazapine vs Rexulti
| Mirtazapine Remove Mirtazapine from your drug comparison | Rexulti Remove Rexulti from your drug comparison |
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| Mirtazapine Remove Mirtazapine from your drug comparison | Rexulti brexpiprazole Remove Rexulti from your drug comparison | ||||||||||||||||
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Mirtazapine may be used in the treatment of depression; however, its use may be limited by its prominent sedative effects. Prescribed for Depression, Major Depressive Disorder. May also be prescribed... View more |
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression. Most people experience some improvement in their symptoms within 1 to 2 weeks of starting... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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6.8
For Depression: 2 month now on mirtazapine and from the state I was in, it has turned around a whole lot. I do have highs that can last a few days or weeks then drop to low sometimes. It's makes me want to eat lots which is good if you need to gain weight. If you take it at the right time you can get sleep and wake up easily. Slight groggy-nesss but nothing heavy like other medications I have tried. Experience a lot of vivid/strong dreams which can wake me up sometimes (not so much a problem for me) I work full time and overall I am able to work my shift and get about my day without millions of thoughts running though my head. |
6.3
For Major Depressive Disorder: Rexulti took time to start working and now I feel better than I have for awhile. I've lost my parents and my ESA in the last 6 years. The downside is the weight gain. I've gained 20 lbs in a short period of time. I can't afford to gain weight, I'm already big. I eat the same things, I don't snack. In comparison, before Rexulti I ate more than I do now and didn't gain weight. It's the weight gain that makes it problematic. For Major Depressive Disorder: I have been on rexulti for 1 month now. It is totally amazing for treatment resistant depression, I haven't felt this good in about 20 years, but am having massive weight gain issues. Can anyone tell me how to get the weight off, as, not eating or exercise is not helping. Would appreciate some advice..thank you |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: severe sedation, constipation, drowsiness, increased serum cholesterol, weight gain, fatigue, insomnia, increased appetite, xerostomia, and decreased appetite. See the full mirtazapine side effects document. |
See the full Rexulti side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all mirtazapine prices |
View all Rexulti prices |
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Generic Availability |
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Yes (this medicine) |
No |
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Dosage Form(s) Available |
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Brand Names |
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| Remeron, Remeron SolTab |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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40 hours |
91 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Summary unavailable. See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
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Drug Interactions |
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A total of 592 drugs are known to interact with mirtazapine:
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A total of 512 drugs are known to interact with Rexulti:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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June 14, 1996 |
July 10, 2015 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Depression: I have been on mitrzapine for nearly 3 years. I started on a low dose and now take 45 mgs at night. The first time I took this medication I was drowsy but so so hungry, I was literally half asleep eating a bag of Crisps. This medication definitely helps me sleep as my anxiety would run wild at night causing sleepless nights, it's definitely great for the sleeping side of things and now that I'm used to it I don't feel it hanging on me the next day. I've rated 7 as this medication has made me gain weight like mad, I find I wake up during the night to eat, they certainly do give you the munchies but I can deal with that side effect if it means having a decent sleep. I've found if I go without this medication my mood severely drops so it's important to never miss a dose.