Comparing Macrobid vs Trimethoprim
| Macrobid | Trimethoprim |
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| Macrobid (nitrofurantoin) | Trimethoprim |
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Prescription only
Prescribed for Urinary Tract Infection, Prevention of Bladder infection, Bladder Infection. Macrobid may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Prevention of Bladder infection, Urinary Tract Infection, Bladder Infection, Otitis Media, Pneumocystis Pneumonia. trimethoprim may also be used for purposes not listed in this medication guide. View more |
Related suggestions Urinary Tract Infection
Bladder Infection
Prevention of Bladder infection (Cystitis Prophylaxis)
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| More about Macrobid (nitrofurantoin) | More about Trimethoprim | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Macrobid has an average rating of 4.5 out of 10 from a total of 792 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 52% reported a negative effect. |
Trimethoprim has an average rating of 2.9 out of 10 from a total of 170 ratings on Drugs.com. 12% of reviewers reported a positive effect, while 73% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: Macrobid side effects in more detail. |
See also: trimethoprim side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Macrobid prices and generic prices |
View all trimethoprim prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other nitrofurantoin brands include: Furadantin, Macrodantin | Primsol | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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1 hour |
14 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 181 drugs are known to interact with Macrobid:
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A total of 128 drugs are known to interact with trimethoprim:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 24, 1991 |
May 30, 1980 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
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N/A |
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| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.