Comparing Lubiprostone vs Trulance
| Lubiprostone | Trulance (plecanatide) |
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| Lubiprostone | Trulance (plecanatide) |
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Prescription only
Prescribed for Irritable Bowel Syndrome with Constipation, Chronic Idiopathic Constipation, Opioid-Induced Constipation, Constipation, Irritable Bowel Syndrome. Lubiprostone may also be used for... View more |
Prescription only
Prescribed for Chronic Idiopathic Constipation, Irritable Bowel Syndrome with Constipation. Trulance may also be used for purposes not listed in this medication guide. |
Related suggestions Chronic Idiopathic Constipation
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| More about Lubiprostone | More about Trulance (plecanatide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Lubiprostone has an average rating of 5.6 out of 10 from a total of 281 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 38% reported a negative effect. |
Trulance has an average rating of 6.1 out of 10 from a total of 279 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Lubiprostone side effects |
View all Trulance side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Lubiprostone prices |
View all Trulance prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Amitiza |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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N/A |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 1 drugs are known to interact with Lubiprostone:
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A total of 1 drugs are known to interact with Trulance:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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January 31, 2006 |
January 19, 2017 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
MiraLAX
MiraLAX (polyethylene glycol) is used as a laxative to treat occasional constipation or irregular ...
Linzess
Linzess (linaclotide) is used to treat chronic idiopathic constipation, irritable bowel syndrome ...
Dupixent
Dupixent is used to treat eczema, eosinophilic or oral-corticosteroid-dependent asthma, chronic ...
Amitiza
Amitiza (lubiprostone) is used to treat chronic constipation and irritable bowel syndrome with ...
Trulance
Trulance (plecanatide) is used to treat chronic idiopathic constipation (CIC) and irritable bowel ...
Ibsrela
Ibsrela (tenapanor) is used for the treatment of irritable bowel syndrome with constipation ...
GlycoLax
GlycoLax is used for bowel preparation, constipation, constipation, acute, irritable bowel ...
Xphozah
Xphozah (tenapanor) is a phosphate absorption inhibitor that is used lower serum phosphorus levels ...
Tenapanor
Tenapanor is used for hyperphosphatemia of renal failure, irritable bowel syndrome with constipation
Plecanatide
Plecanatide is used for chronic idiopathic constipation, constipation, irritable bowel syndrome ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.