Comparing Letrozole vs Tamoxifen
| Letrozole | Tamoxifen |
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| Letrozole | Tamoxifen |
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Prescription only
Letrozole (brand name Femara) is a treatment that may be used to reduce the risk of breast cancer recurrence in postmenopausal women and also to increase the chance of ovulation in women with... View more |
Prescription only
Prescribed for Breast Cancer - Adjuvant, Breast Cancer - Metastatic, Breast Cancer, Breast Cancer - Male, Breast Cancer - Palliative, Breast Cancer - Prevention, McCune-Albright Syndrome, Precocious... View more |
Related suggestions Breast Cancer
Breast Cancer, Adjuvant
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| More about Letrozole | More about Tamoxifen | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Letrozole has an average rating of 6.5 out of 10 from a total of 367 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 21% reported a negative effect. |
Tamoxifen has an average rating of 5.6 out of 10 from a total of 97 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Letrozole side effects |
View all Tamoxifen side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Letrozole prices |
View all Tamoxifen prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Femara | Soltamox | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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48 hours |
231 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 121 drugs are known to interact with Letrozole:
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A total of 459 drugs are known to interact with Tamoxifen:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 25, 1997 |
December 30, 1977 |
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| WADA Class View classifications | |||||||||||||||||
| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.