Comparing Letrozole vs Tamoxifen
| Letrozole | Tamoxifen |
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| Letrozole | Tamoxifen |
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Prescription only
Letrozole is a treatment that may be used to reduce the risk of breast cancer recurrence in postmenopausal women and also to increase the chance of ovulation in women with polycystic ovary syndrome... View more |
Prescription only
Prescribed for Breast Cancer - Male, Breast Cancer - Adjuvant, Breast Cancer - Metastatic, Breast Cancer, Breast Cancer - Palliative, McCune-Albright Syndrome, Precocious Puberty. May also be... View more |
Related suggestions Breast Cancer
Breast Cancer, Metastatic
Breast Cancer, Adjuvant
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| More about Letrozole | More about Tamoxifen | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Letrozole has an average rating of 6.4 out of 10 from a total of 328 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 23% reported a negative effect. |
Tamoxifen has an average rating of 5.5 out of 10 from a total of 93 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Commonly reported side effects include:
See also: letrozole side effects in more detail. |
Commonly reported side effects include:
See also: tamoxifen side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all letrozole prices |
View all tamoxifen prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Femara | Soltamox | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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48 hours |
231 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 101 drugs are known to interact with letrozole:
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A total of 394 drugs are known to interact with tamoxifen:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 25, 1997 |
December 30, 1977 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.