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Generic name: tamoxifenta-MOX-i-fen ]
Drug classes: Hormones / antineoplastics, Selective estrogen receptor modulators

Medically reviewed by on Jun 13, 2023. Written by Cerner Multum.

What is Soltamox?

Soltamox is used to treat some types of breast cancer in men and women. This medicine is also used to lower a woman's chance of developing breast cancer if she has a high risk (such as a family history of breast cancer).

Soltamox may also be used for purposes not listed in this medication guide.

Soltamox side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Soltamox can increase your risk of stroke or blood clots. Call your doctor at once if you have:

Also call your doctor at once if you have:

Common side effects of Soltamox may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Taking Soltamox may increase your risk of uterine cancer, liver cancer, stroke, or a blood clot in the lung, which can be fatal.

Before taking this medicine

You should not use Soltamox if you are allergic to it.

May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use birth control while using Soltamox and for at least 2 months after your last dose. Tell your doctor if you become pregnant.

To prevent pregnancy while using Soltamox, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge. Avoid using hormonal birth control, including birth control pills, injections, implants, skin patches, and vaginal rings.

You should not use Soltamox to reduce your risk of breast cancer if you also take warfarin (Coumadin, Jantoven).

Tell your doctor if you have ever had:

Taking Soltamox may increase your risk of uterine cancer, liver cancer, stroke, or a blood clot in the lung, which can be fatal. Talk with your doctor about your own risks.

Do not breastfeed while using Soltamox, and for at least 3 months after your last dose.

Not approved for use by anyone younger than 18 years old.

How should I take Soltamox?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Take with or without food.

You may need to keep using this medicine for 5 to 10 years.

Have regular physical exams and mammograms, and self-examine your breasts for lumps on a monthly basis while using Soltamox.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Soltamox.

Store at room temperature away from moisture, heat, and light. Do not refrigerate or freeze. Throw away any leftover liquid medicine 3 months after you first opened the bottle.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Soltamox?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect Soltamox?

Many drugs can affect Soltamox, and some drugs should not be used at the same time. Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

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Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.