Comparing Isotretinoin vs Retin-A
| Isotretinoin | Retin-A (tretinoin) |
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| Isotretinoin | Retin-A (tretinoin) |
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Prescription only
Prescribed for Rosacea, Acne, Granuloma Annulare, Acute Nonlymphocytic Leukemia, Pityriasis rubra pilaris, Melanoma - Metastatic. Isotretinoin may also be used for purposes not listed in this medication guide. View more |
Prescription only
Prescribed for Photoaging of the Skin, Lichen Sclerosus, Acne, Necrobiosis Lipoidica Diabeticorum. Retin-A may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Isotretinoin | More about Retin-A (tretinoin) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Isotretinoin has an average rating of 7.9 out of 10 from a total of 1060 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 13% reported a negative effect. |
Retin-A has an average rating of 7.9 out of 10 from a total of 97 ratings on Drugs.com. 77% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Isotretinoin side effects |
View all Retin-A side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Isotretinoin prices |
View all Retin-A prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Absorica, Absorica LD, Accutane, Amnesteem, Claravis, Myorisan, Sotret, Zenatane | Other tretinoin brands include: Altinac, Altreno, Atralin, Avita, Obagi, Refissa, Renova, Retin A Micro, Retin-A and Renova View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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32 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 140 drugs are known to interact with Isotretinoin:
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A total of 12 drugs are known to interact with Retin-A:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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May 07, 1982 |
October 20, 1971 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.