Ibrance Alternatives Compared
| Ibrance | Keytruda | Anastrozole |
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| Ibrance (palbociclib) | Keytruda (pembrolizumab) | Anastrozole |
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Prescription only
Ibrance is a CDK4/6 inhibitor that may be used to treat advanced or metastatic hormone-receptor-positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancer in combination... View more |
Prescription only
Keytruda is a type of immunotherapy that helps boost the immune system's response against cancer. It may be used to treat many different types of cancer in adults and children and is given by... View more |
Prescription only
Anastrozole is a medication that may be used to treat postmenopausal breast cancer and works by lowering estrogen levels in the body. It is usually taken for five years and hot flushes are the most... View more |
Related suggestions |
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| More about Ibrance (palbociclib) | More about Keytruda (pembrolizumab) | More about Anastrozole | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Ibrance has an average rating of 6.7 out of 10 from a total of 77 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 32% reported a negative effect. |
Keytruda has an average rating of 4.0 out of 10 from a total of 199 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 62% reported a negative effect. |
Anastrozole has an average rating of 5.2 out of 10 from a total of 229 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 37% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: Ibrance side effects in more detail. |
See also: Keytruda side effects in more detail. |
See also: anastrozole side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Ibrance prices |
View all Keytruda prices |
View all anastrozole prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
Arimidex | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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29 hours |
624 hours |
50 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 444 drugs are known to interact with Ibrance:
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A total of 19 drugs are known to interact with Keytruda:
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A total of 20 drugs are known to interact with anastrozole:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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February 03, 2015 |
N/A |
December 27, 1995 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.