Comparing Fentanyl Transdermal System vs Xtampza ER

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Fentanyl Transdermal System (fentanyl)	Xtampza ER (oxycodone)	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Fentanyl Transdermal System (fentanyl)	Xtampza ER (oxycodone)	Enter another drug to compare
Prescription only Prescribed for Chronic Pain, Pain. Fentanyl Transdermal System may also be used for purposes not listed in this medication guide.	Prescription only Prescribed for Chronic Pain, Pain. Xtampza ER may also be used for purposes not listed in this medication guide.	Related suggestions Pain Tramadol Gabapentin Ibuprofen Acetaminophen Oxycodone Tylenol Chronic Pain Oxycodone Tramadol Dilaudid Cymbalta OxyContin Acetaminophen / oxycodone
More about (fentanyl)	More about Xtampza ER (oxycodone)
Ratings & Reviews
Fentanyl Transdermal System has an average rating of 7.6 out of 10 from a total of 107 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 12% reported a negative effect.	Xtampza ER has an average rating of 3.9 out of 10 from a total of 169 ratings on Drugs.com. 24% of reviewers reported a positive effect, while 62% reported a negative effect.
View all 107 reviews	View all 169 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Sweating (13.1%) Pain (7.5%) Withdrawal (5.6%) Dry mouth (3.7%) Nausea (3.7%) Chills (2.8%) Constipation (2.8%) View all Fentanyl Transdermal System side effects	Nausea (11.8%) Headaches (7.7%) Dizziness (4.7%) Nightmares (4.7%) Pain (4.7%) Weight gain (4.1%) Withdrawal (4.1%) View all Xtampza ER side effects
Drug Class
Opioids (narcotic analgesics)	Opioids (narcotic analgesics)
Generic Availability
Lower cost generic approved	No lower cost generic approved
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
N/A	N/A
Brand Names
Other fentanyl brands include: Actiq, Duragesic, Fentora, Lazanda, Subsys	Other oxycodone brands include: Dazidox, Endocodone, ETH-Oxydose, Oxaydo, OxyContin, Oxydose, Oxyfast, Roxicodone, RoxyBond View more
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
8.7 hours	5.6 hours
CSA Schedule ¹ View glossary of CSA terms
2 High potential for abuse Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.	2 High potential for abuse Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
Pregnancy Category
C Category C Risk cannot be ruled out See the full pregnancy warnings document.	N Category N Not classified See the full pregnancy warnings document.
Drug Interactions
A total of 643 drugs are known to interact with Fentanyl Transdermal System: 260 major drug interactions (986 brand and generic names) 378 moderate drug interactions (1483 brand and generic names) 5 minor drug interactions (109 brand and generic names)	A total of 626 drugs are known to interact with Xtampza ER: 214 major drug interactions (781 brand and generic names) 408 moderate drug interactions (1584 brand and generic names) 4 minor drug interactions (100 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Do not use alcohol or medications that contain alcohol while you are receiving treatment with... View more	Do not use alcohol or medications that contain alcohol while you are receiving treatment with... View more
Disease Interactions
Impaired GI motility Infectious diarrhea Prematurity Acute alcohol intoxication Drug dependence Hypotension Intracranial pressure Respiratory depression Gastrointestinal obstruction Fever Adrenal insufficiency Liver disease Renal dysfunction Seizure disorders Urinary retention Arrhythmias Biliary tract disease	Impaired GI motility Infectious diarrhea Prematurity Acute alcohol intoxication Drug dependence Hypotension Intracranial pressure Respiratory depression Gastrointestinal obstruction Adrenal insufficiency Liver disease Renal dysfunction Seizure disorders Urinary retention Arrhythmias Biliary tract disease
First Approval Date
N/A	April 26, 2016
WADA Class View classifications
S7 - Narcotics	S7 - Narcotics
More Information
Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings Support group	Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings Drug images Support group En español
Patient Resources
N/A	Xtampza ER uses
Professional Resources
N/A	Prescribing information
Related Treatment Guide
Chronic Pain Pain	Chronic Pain Pain

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Fentanyl Transdermal System vs Xtampza ER

See also:

Paracetamol

Tylenol

Ozempic

Cymbalta

Naproxen

Oxycodone

Amitriptyline

Duloxetine

Tramadol

Ibuprofen

Further information

Comparing Fentanyl Transdermal System vs Xtampza ER

See also:

Further information

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