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Comparing Estarylla vs Kyleena

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Estarylla Remove Estarylla from your drug comparison	Kyleena Remove Kyleena from your drug comparison	Add another drug to compare

Estarylla ethinyl estradiol / norgestimate

Kyleena levonorgestrel

Prescribed for Acne, Birth Control, Endometriosis, Abnormal Uterine Bleeding, Gonadotropin Inhibition. May also be prescribed off label for Ovarian Cysts.

Prescribed for Birth Control. Kyleena may also be used for purposes not listed in this medication guide.

Prescription only

Ratings & Reviews

View all 405 reviews

View all 1403 reviews

Drug Class

Contraceptives

Side Effects

See the full Estarylla side effects document.

See the full Kyleena side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	84 each
Dosage	35 mcg-0.25 mg
Per Unit^*	$0.59 - $0.73
Cost^*	$49.53 - $61.58

View all Estarylla prices and generic prices

Quantity	1 device
Dosage	19.5 mg
Per Unit^*	$1,052.75
Cost^*	$1,052.75

View all Kyleena prices and generic prices

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Generic Availability

Yes

Dosage Form(s) Available

Oral tablet

Intrauterine device

Brand Names

Other ethinyl estradiol / norgestimate brands include: Femynor, Mili, Mono-Linyah, Nymyo, Previfem, Sprintec, Tri Femynor, Tri-Estarylla, Tri-Linyah, Tri-Lo-Estarylla, Tri-Lo-Marzia, Tri-Lo-Mili, Tri-Lo-Sprintec, Tri-Mili, Tri-Nymyo, Tri-Previfem, Tri-Sprintec, Tri-VyLibra, Tri-Vylibra Lo, VyLibra View more Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, BionaFem, EContra EZ, EContra One-Step, Fallback Solo, Liletta, Mirena, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Plan B One-Step, PostDay One-Step, Preventeza, React, Skyla, Take Action View more

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

N/A

45 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (2)

N/A

Drug Interactions

A total of 412 drugs are known to interact with Estarylla:

34 major drug interactions (95 brand and generic names)
333 moderate drug interactions (1197 brand and generic names)
45 minor drug interactions (480 brand and generic names)

A total of 214 drugs are known to interact with Kyleena:

31 major drug interactions (87 brand and generic names)
171 moderate drug interactions (543 brand and generic names)
12 minor drug interactions (33 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Grapefruit juice may increase the blood levels of certain medications such as norgestimate. You... View more

Grapefruit juice may increase the blood levels of certain medications such as levonorgestrel. You... View more

Disease Interactions

First Approval Date

N/A

September 16, 2016

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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