Skip to Content
Print Share

Comparing Enbrel vs Orencia

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Enbrel Remove Enbrel from your drug comparison Orencia Remove Orencia from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Enbrel etanercept Remove Enbrel from your drug comparison Orencia abatacept Remove Orencia from your drug comparison

Enbrel is a subcutaneous injection that is usually self-administered once or twice a week for inflammatory conditions such as rheumatoid arthritis, psoriasis, psoriatic arthritis, or ankylosing... View more

Prescribed for Rheumatoid Arthritis, Psoriatic Arthritis, Juvenile Idiopathic Arthritis. Orencia may also be used for purposes not listed in this medication guide.

Prescription only

Prescription only

Ratings & Reviews

Recent helpful reviews

View all 240 reviews

View all 49 reviews

Drug Class

Side Effects

Common side effects include: infection, and injection site reaction.

See the full Enbrel side effects document.

Common side effects include: headache, and nasopharyngitis.

See the full Orencia side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 0.98 mL
Dosage 50 mg/mL
Per Unit* $689.13
Cost* $675.35

View all Enbrel prices

Quantity 1 powder for injection
Dosage 250 mg
Per Unit* $1,236.79 - $1,292.02
Cost* $1,236.79 - $1,292.02

View all Orencia prices

Get free Discount Card

Get free Discount Card

Generic Availability

No

No

Dosage Form(s) Available
  • Subcutaneous kit
  • Subcutaneous solution
  • Intravenous powder for injection
  • Subcutaneous solution

Brand Names
Other etanercept brands include: Erelzi, Eticovo

N/A

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

300 hours

600 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (6)

N/A

Drug Interactions

A total of 390 drugs are known to interact with Enbrel:

  • 231 major drug interactions (694 brand and generic names)
  • 152 moderate drug interactions (597 brand and generic names)
  • 7 minor drug interactions (33 brand and generic names)

A total of 108 drugs are known to interact with Orencia:

  • 34 major drug interactions (90 brand and generic names)
  • 67 moderate drug interactions (218 brand and generic names)
  • 7 minor drug interactions (33 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

November 02, 1998

December 23, 2005

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer