Comparing Clozapine vs Seroquel
Clozapine Remove Clozapine from your drug comparison | Seroquel Remove Seroquel from your drug comparison |
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Clozapine Remove Clozapine from your drug comparison | Seroquel quetiapine Remove Seroquel from your drug comparison | ||||||||||||||||
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Prescribed for Schizophrenia. May also be prescribed off label for Borderline Personality Disorder, Paranoid Disorder. |
Seroquel is an antipsychotic that helps to calm and relieve psychotic thoughts. It is often given because it is quite sedating; however, care is needed because it also lowers blood pressure.... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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7.6
For Schizophrenia: My son starting showing signs of psychosis right after his 14th bday. Diagnosed with schizophrenia 6 months later. He was in a constant state of his own reality and heard voices on a regular basis. Seroqel, Zyprexa, Invega, and Ability did nothing for him. His psychiatrist prescribed Clozapine as a last resort. I won't allow his dosage any higher than 300mg per day for now since the side effects worry me. This drug has been a lifesaver to allow him to participate in the regular world and quiet the voices where he can focus on real ppl. It makes him drowsy so he takes it at night. Weight gain is significant but most antipsychotics will do this. Regular blood monitoring to make sure his WBC stays normal. So good, so far. |
7.0
For Bipolar Disorder: If you have Bipolar Disorder type II, please learn as much as you can about this condition from professional, reputable sources so you can make informed decisions about treatment and management options. This is a treatable, manageable illness, take hope in that. After 20+ years struggling to "cure" myself "naturally" & being miserable, dangerously depressed & dysfunctional, I finally decided to try psych medication. I found a doctor who SPECIALISES in this disorder and is up to date with the latest research findings in this specific condition. If you don't like your current GP or Psych's attitude, find someone else! I started a combo of Lamictal (AM & PM) & Seroquel (Only PM - makes you drowsy). I kept a daily mood diary & it took 3 months for my mood to fully stabilise. To help the bipolar depression, we added bupropion & N-Acetyl Cysteine, a supplement (all based on clinical research!). For 5 years now, I’ve had my life back. Deciding to take this medication saved my life. For Bipolar Disorder: I was hospitalized 17 years ago with a major manic mixed episode. It was worst thing on earth. Was given 200 milligrams of serequel and it calmed down the demons. Tapered the dose down in months time come and stayed successfully at 50 milligrams for following 17 years. Long term side effects began with bloods changed, elevated blood sugar and triglycerides. Weaned and got off it, took several weeks. Feeling better with more clarity and regular movements now. Those two weeks of getting out of my system caused side effects of weird dreams, body aches and mood swings. Hard time sleeping. Increases over the counter supplements and made sure my life was low key until things settled. I’m grateful for the med. If not for the side effects which would have led to diabetes I would have remained in it. But I believe in the beginning it saved my life. |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: hypotension, fever, tachycardia, constipation, dizziness, headache, nausea, sedated state, vomiting, and weight gain. See the full clozapine side effects document. |
Common side effects include: asthenia, constipation, dizziness, drowsiness, headache, increased serum cholesterol, increased serum triglycerides, increased thyroid stimulating hormone level, and xerostomia. See the full Seroquel side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all clozapine prices |
View all Seroquel prices and generic prices |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Clopine, Clozapine Synthon, Clozaril, Denzapine, FazaClo, Versacloz | Other quetiapine brands include: Seroquel XR | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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10.3 hours |
6 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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FDA Alerts |
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Drug Interactions |
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A total of 819 drugs are known to interact with clozapine:
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A total of 649 drugs are known to interact with Seroquel:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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September 26, 1989 |
September 26, 1997 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Schizophrenia: My son is in his early 20'and has schitsoaffective dissorder.He has been on at least five different medications for his illness. And nothing seem to help or if it did it lasted only for a little while or he had severe allergic reactions. So he started clozapine/clozaril around a month ago. And it has made a big difference .The voices gradually are going away. He can actually sit and watch TV and have a conversation. He is enjoying things again. We do go for blood work every week which he does not mind. This medicine is working and I'm hoping his blood work comes back good every week, Because to see him getting better is such a relief . And I am hopeful for a happy productive life for him. Things are looking up.