Comparing Clindamycin Topical vs Metronidazole Topical

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Clindamycin topical

Metronidazole topical

Prescribed for Bacterial Vaginitis, Perioral Dermatitis, Acne. clindamycin topical may also be used for purposes not listed in this medication guide.

Prescribed for Rosacea, Perioral Dermatitis, Bacterial Vaginitis. May also be prescribed off label for Balanoposthitis.

Prescription only

Ratings & Reviews

View all 210 reviews

View all 290 reviews

Drug Class

Side Effects

Commonly reported side effects include: vulvovaginal candidiasis.

See the full clindamycin topical side effects document.

See the full metronidazole topical side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	30 mL
Dosage	1%
Per Unit^*	$0.83 - $1.18
Cost^*	$25.04 - $35.43

View all clindamycin topical prices

Quantity	55 gram(s)
Dosage	1%
Per Unit^*	$2.64
Cost^*	$145.38

View all metronidazole topical prices

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Generic Availability

Yes (this medicine)

Dosage Form(s) Available

Topical foam
Topical gel
Topical lotion
Topical solution
Topical swab
Vaginal cream

Topical cream
Topical gel
Topical lotion
Vaginal gel with applicator

Brand Names

C/T/S, Cleocin Ovules, Cleocin T, Cleocin Vaginal, Clinda-Derm, Clindacin ETZ, Clindacin P, Clindacin PAC, Clindagel, Clindamax, ClindaReach Pledget, Clindesse, Clindets, Clindets Pledget, Evoclin View more MetroCream, MetroGel, MetroGel-Vaginal, MetroLotion, Noritate, Nuvessa, Rosaclear, Rosadan, Vandazole View more

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

N/A

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full Pregnancy Warnings document.

Category B No proven risk in humans

See the full Pregnancy Warnings document.

Drug Interactions

A total of 12 drugs are known to interact with clindamycin topical:

12 moderate drug interactions (25 brand and generic names)

A total of 8 drugs are known to interact with metronidazole topical:

1 major drug interactions (2 brand and generic names)
7 moderate drug interactions (26 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Consumption of alcoholic beverages or products containing alcohol or propylene glycol during... View more

Disease Interactions

Colitis

First Approval Date

July 09, 1980

November 22, 1988

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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