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Clindamycin topical Pregnancy and Breastfeeding Warnings

Clindamycin topical is also known as: C/T/S, Cleocin Ovules, Cleocin T, Cleocin Vaginal, Clinda-Derm, ClindaReach Pledget, Clindacin ETZ, Clindacin P, Clindacin PAC, Clindagel, Clindamax, Clindesse, Clindets, Clindets Pledget, Evoclin, Pledgaclin

Clindamycin topical Pregnancy Warnings

This drug should be used during pregnancy only if clearly needed. AU TGA pregnancy category: A US FDA pregnancy category: B

Animal studies have failed to reveal evidence of fetal harm when given oral or parenteral doses up to 300 mg/kg/day. Approximately 1.1% of pregnant patients in their second trimester given the vaginal cream experienced abnormal labor, compared to 0.5% of patients given placebo. There are no controlled data in the first trimester of human pregnancy. AU TGA pregnancy category A: Drugs which have been taken by a large number of pregnant women and women of childbearing age without any proven increase in the frequency of malformations or other direct or indirect harmful effects on the fetus having been observed. US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

See references

Clindamycin topical Breastfeeding Warnings

This drug is excreted into breastmilk when given orally or intravenously.

Use is not recommended and a decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother. Excreted into human milk: Unknown Excreted into animal milk: Unknown Comment: The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. "Product Information. Cleocin vaginal cream (clindamycin)." Pharmacia and Upjohn, Kalamazoo, MI.
  2. "Product Information. Cleocin T (clindamycin)." Pharmacia and Upjohn, Kalamazoo, MI.
  3. "Product Information. Clindesse (clindamycin topical)." Ther-Rx Corporation, Bridgeton, MO.
  4. "Product Information. Evoclin (clindamycin topical)." Connetics Inc, Palo Alto, CA.
  5. Cerner Multum, Inc. "Australian Product Information." O 0
  6. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  7. "Product Information. Cleocin Vaginal Ovules (clindamycin topical)" Pharmacia and Upjohn, Kalamazoo, MI.

References for breastfeeding information

  1. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):
  2. "Product Information. Evoclin (clindamycin topical)." Connetics Inc, Palo Alto, CA.
  3. "Product Information. Cleocin Vaginal Ovules (clindamycin topical)" Pharmacia and Upjohn, Kalamazoo, MI.
  4. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  5. Cerner Multum, Inc. "Australian Product Information." O 0
  6. "Product Information. Clindesse (clindamycin topical)." Ther-Rx Corporation, Bridgeton, MO.
  7. "Product Information. Cleocin vaginal cream (clindamycin)." Pharmacia and Upjohn, Kalamazoo, MI.
  8. "Product Information. Cleocin T (clindamycin)." Pharmacia and Upjohn, Kalamazoo, MI.

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