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Clindamycin topical and Yeast Infection: What Users Say

Brand names: Clindagel, Cleocin T, Clindamax, Clindesse, ClindaReach Pledget, Clindacin, Clindets, Cleocin Vaginal, C/T/S, Clinda-Derm, Clindets Pledget, Cleocin Ovules, Clindacin P, Clindacin ETZ, Xaciato, Evoclin Clindacin PAC …show all brand names

Yeast infection: mentioned by 9 users (3.9%)

Based on user experiences from 232 Clindamycin topical reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 18.1%
itching 7.8%
acne 5.2%
dryness 4.7%
yeast infection 3.9%
dry skin 3.4%
oily skin 3.4%
rash 3.4%
redness 3.0%
diarrhea 2.6%

Reviews for Clindamycin topical

Commonly mentioned side effects
  • Anonymous
  • Taken for less than 1 month
  • December 26, 2020

For Bacterial Vaginosis "I had a bad episode of BV and was first prescribed Metronidazole, but soon after that treatment, I too began having a yeast infection. After being treated for the yeast (I think it was Flagyl), my BV returned. I have since then been prescribed Clindamycin, but for whatever reason, it won’t stay in me! I’ve used it as prescribed (bedtime only), but the next morning it’s coming out with my pee, and when I wipe, it is all on the tissue! Has anyone else experienced this? If so, is there not enough medication left up in me to actually begin working???"

7 / 10
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  • Lon...
  • Taken for less than 1 month
  • February 4, 2020

For Bacterial Vaginosis "I'm reading comments, and no one has said anything about the white cream turning brown by the end of the day. Had anyone experienced this? This is my 1st time taking this. Only did one insertion after reading the reviews, will not do another in fear of the worst yeast infection of my life. (Yikes) don't feel like dealing with a burning vagina, y'know?? I took my 1st cream dosage last night, and as of tonight, it's starting to come out, but it's turned brown. Who else has dealt with this?"

2 / 10
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30 Report
  • Ang...
  • January 27, 2020

Clindamycin topical for Bacterial Vaginosis "I read reviews about Clindesse and was very skeptical. I used it, and the foul odor went away in a matter of hours. I read that it gives you a yeast infection, so I took something to prevent it. Fast forward...Clindesse is a very powerful antibiotic. It literally cleans out all of the old bacteria that metronidazole didn't get. I'm on day 5, and it's still excreting bacteria, but not like in the beginning. I finally feel a sense of relief. Everyone's chemistry is different, so it may work on one woman differently than another. I'd absolutely try it again."

10 / 10
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20 Report
  • jcv...
  • Taken for less than 1 month
  • August 2, 2014

Clindamycin topical for Bacterial Vaginosis "My doc gave me Clindesse as a last resort to my 6-month vaginal discharge issue. Luckily, she gave me a free sample. I inserted it on Wednesday night, and by Friday afternoon, I had a raging yeast infection! Called the doc back, and she prescribed Diflucan to counteract the Clindesse-induced yeastie. This changed my ongoing symptoms for the worse! Ladies, I sincerely hope this med works for most of you, but for me, it didn't. For being someone who has never had side effects of any meds, this was certainly a first for me."

2 / 10
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44 Report
  • Anonymous
  • January 19, 2017

Clindamycin topical for Bacterial Vaginosis "This med was prescribed to me 3 months ago for vaginal 'E. coli.' I did not have any symptoms at all of b.v. or 'E. coli' until I used it! I have had extreme issues! A shingles outbreak the days after using it, burning, itching, swelling, oral and vaginal yeast infection. My immune system has been severely low, and I cannot seem to get better. This med ruined my life! I went to the doc feeling normal, but after using Clindesse, I feel like I have AIDS! I was tested last year, and I was negative, so now 3 months later, and my body is all messed up. Worst med I have ever taken!"

1 / 10
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22 Report

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  • Anonymous
  • Taken for less than 1 month
  • December 16, 2019

Clindamycin topical for Bacterial Vaginosis "I was prescribed Clindesse to treat BV. Over the last couple of years, I've been dealing with recurring BV. Up until this prescription, I've always been prescribed Flagyl. Apparently, my body has become immune to it, so my doctor wanted me to try this. It worked to treat the BV. The BV was completely gone in 2 days. However, I am now dealing with one of the WORST yeast infections I've ever had in my life. I've taken 2 doses of Diflucan, and it's not going anywhere. Attempting a Monistat 1-day cream tonight. I will never use this medication again!"

1 / 10
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  • Ash...
  • Taken for less than 1 month
  • February 4, 2022

For Bacterial Vaginosis "Yes, it’s messy. Yes, it’s annoying. But it works. I have been prescribed the metronidazole pills, which are more convenient but make me sick to my stomach at times and dry my vagina out. I also have tried Metro Gel, which gave me a yeast infection so bad I could have baked a loaf of bread! The clindamycin cream leaves my vag moist and clear of infection or odor that doesn’t return. You have to use it properly, and it will work."

10 / 10
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  • Sic...
  • January 11, 2022

Clindamycin topical for Bacterial Vaginosis "I’ve never suffered with BV, but after having an IUD and an unfaithful partner, I developed a severe case of BV. After 2 rounds of Clindesse and a dose of Tinidazole, I am much better! I got rid of them both! It didn’t give me a yeast infection, but I loaded up on probiotics instead of my normal Diflucan."

10 / 10
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  • Not...
  • July 20, 2016

Clindamycin topical for Bacterial Vaginosis "Easy to use, but gave me a horrendous yeast infection. Would rather have taken Flagyl."

3 / 10
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7 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.