Comparing Casodex vs Lupron Depot

For Prostate Cancer: My PSA had reached 39.7 and I underwent surgical castration on March 19 2009 in Delhi India where I was on holiday. I returned to the UK on 23 March. My consultant prescribed Casodex 50mg once per day for my remaining lifetime. I am 79 years old and tolerated the surgery well. On 13 May my PSA level had dropped to 0.6 and on the 13 July my PSA result was so low that it was non-recordable. I have suffered a recent bout of pneumonia, and I have frequent hot flashes, but otherwise I feel much better than I did before surgery and the Casodex seems to be doing it's job. I take no other medicine than the Casodex.

For Prostate Cancer: I have taken Casodex for years and PSA stays around 3.7. No operation. Side effect is enlarged breasts. Now 79 years old and swimming a mile a day. Feel strong and doing well.

For Endometriosis: I've finished my third cycle of lupron for endometriosis and it kicked my butt ! Each cycle includes an injection each month, for 6 months. Once I finish Lupron, I slowly have periods and each month the pain gets stronger. Last time was bad, but nothing like this. There's no way of describing it other then "Roid rage", I couldn't control my emotions. 2 1/2 months I was manic, I'm talking fighting fits of rage and sobbing on the floor. which is nothing like myself, I'm almost emotionless. Hot flashes, hair thinning, loss of sex drive. That last one which I hope doesn't affect you, surprisingly is one of the worst. Gained 30 lbs over 6 mths while dieting, Even with an extremely strict diet I have only managed to loose 2 pounds and it's been 2 and a half months since my last injection. All in all I'm not sure if I will go through another treatment of Lupron as all the side effects that affected me seem to get more intense each time.

For Endometriosis: I had a very similar experience to Lora C. I was a mess on Lupron and very much not myself. I couldn't control my emotions, I was either dead inside or crying, there was no in between. My night sweats were awful and I was mean all the time. The worst part was probably my memory. I had no recollection of anyone's name, I could recognize their face and the fact that I definitely know them, but never their names if I had met them after I was on Lupron. The shot also hurts like anything and hot flashes are real. I was consistently warm all of the time. Summer was unbearable. Also, the first few months were the worst endo pain I had ever felt. It was terrible. It finally went away after about month 4 or 5 and I was in a normal range of just feeling pressure down there. It wasn't nearly as painful, but always present.