Comparing Buprenorphine vs Probuphine
| Buprenorphine | Probuphine (buprenorphine) |
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| Buprenorphine | Probuphine (buprenorphine) |
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Prescription only
Buprenorphine is a potent analgesic that should be only used to treat moderate to severe pain or for the treatment of opioid addiction under strict conditions. Different formulations of the drug... View more |
Prescription only
Probuphine is a buprenorphine implant that lasts for 6 months and may be considered in people who are stable on sublingual/buccal forms of buprenorphine providing they meet certain other criteria... View more |
Related suggestions Opioid Use Disorder
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| More about Buprenorphine | More about Probuphine (buprenorphine) | ||||||||
| Ratings & Reviews | |||||||||
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Buprenorphine has an average rating of 6.7 out of 10 from a total of 1149 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 25% reported a negative effect. |
Probuphine has an average rating of 10.0 out of 10 from a total of 3 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Buprenorphine side effects |
View all Probuphine side effects |
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| Drug Class | |||||||||
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None |
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| Generic Availability | |||||||||
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Lower cost generic |
Lower cost generic approved | ||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Buprenorphine prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Belbuca, Brixadi, Buprenex, Butrans, Sublocade | Other buprenorphine brands include: Belbuca, Brixadi, Buprenex, Butrans, Sublocade | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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48 hours |
48 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 717 drugs are known to interact with Buprenorphine:
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A total of 717 drugs are known to interact with Probuphine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 29, 1981 |
May 26, 2016 |
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| WADA Class View classifications | |||||||||
| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.