Comparing Buprenorphine vs Probuphine
| Buprenorphine | Probuphine (buprenorphine) |
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| Buprenorphine | Probuphine (buprenorphine) |
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Prescription only
Buprenorphine is a potent analgesic that should be only used to treat moderate to severe pain or for the treatment of opioid addiction under strict conditions. Different formulations of the drug... View more |
Prescription only
Probuphine is a buprenorphine implant that lasts for 6 months and may be considered in people who are stable on sublingual/buccal forms of buprenorphine providing they meet certain other criteria... View more |
Related suggestions Opioid Use Disorder
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| More about Buprenorphine | More about Probuphine (buprenorphine) | ||||||||
| Ratings & Reviews | |||||||||
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Buprenorphine has an average rating of 6.7 out of 10 from a total of 1147 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 25% reported a negative effect. |
Probuphine has an average rating of 10.0 out of 10 from a total of 3 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Buprenorphine side effects |
View all Probuphine side effects |
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| Drug Class | |||||||||
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None |
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| Generic Availability | |||||||||
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Lower cost generic |
Lower cost generic approved | ||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Buprenorphine prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Belbuca, Brixadi, Buprenex, Butrans, Sublocade | Other buprenorphine brands include: Belbuca, Brixadi, Buprenex, Butrans, Sublocade | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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48 hours |
48 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 717 drugs are known to interact with Buprenorphine:
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A total of 717 drugs are known to interact with Probuphine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 29, 1981 |
May 26, 2016 |
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| WADA Class View classifications | |||||||||
| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.