Brexanolone Alternatives Compared
Brexanolone | Zoloft | Sertraline |
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Brexanolone | Zoloft (sertraline) | Sertraline |
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Prescription only
Prescribed for Postpartum Depression. brexanolone may also be used for purposes not listed in this medication guide. |
Prescription only
Zoloft is a brand name for sertraline which is an effective antidepressant with less potential for drowsiness than many other antidepressants. It belongs to the group of medicines called selective... View more |
Prescription only
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Headaches, nausea, diarrhea, weight loss, insomnia, tremors, and sexual dysfunction are the... View more |
Related suggestions Postpartum Depression
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More about Brexanolone | More about Zoloft (sertraline) | More about Sertraline | ||||||||||||||||
Ratings & Reviews | ||||||||||||||||||
Be the first to share your experience with this drug. |
Zoloft has an average rating of 7.3 out of 10 from a total of 1952 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 19% reported a negative effect. |
Sertraline has an average rating of 7.3 out of 10 from a total of 4484 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 18% reported a negative effect. |
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Drug Class | ||||||||||||||||||
Side Effects | ||||||||||||||||||
See also: brexanolone side effects in more detail. |
See also: Zoloft side effects in more detail. |
See also: sertraline side effects in more detail. |
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Generic Availability | ||||||||||||||||||
N/A |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Zoloft prices |
View all sertraline prices |
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Dosage Forms Available | ||||||||||||||||||
N/A |
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Brand Names | ||||||||||||||||||
Zulresso |
N/A |
Zoloft | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
9 hours |
66 hours |
66 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||
A total of 273 drugs are known to interact with brexanolone:
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A total of 670 drugs are known to interact with Zoloft:
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A total of 670 drugs are known to interact with sertraline:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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Disease Interactions | ||||||||||||||||||
First Approval Date | ||||||||||||||||||
March 19, 2019 |
December 30, 1991 |
December 30, 1991 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||
Patient resources | ||||||||||||||||||
Professional Resources | ||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.