Comparing Apri vs Skyla
| Apri (desogestrel / ethinyl estradiol) | Skyla (levonorgestrel) |
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| Apri (desogestrel / ethinyl estradiol) | Skyla (levonorgestrel) |
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Prescription only
Prescribed for Birth Control. Apri may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Birth Control. Skyla may also be used for purposes not listed in this medication guide. |
Related suggestions Birth Control
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| More about Apri (desogestrel / ethinyl estradiol) | More about Skyla (levonorgestrel) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Apri has an average rating of 5.4 out of 10 from a total of 458 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 36% reported a negative effect. |
Skyla has an average rating of 6.9 out of 10 from a total of 1540 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Lower cost generic approved | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Apri prices |
View all Skyla prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other desogestrel / ethinyl estradiol brands include: Azurette, Bekyree, Caziant, Cyclessa, Cyred, Cyred EQ, Desogen, Emoquette, Enskyce, Isibloom, Juleber, Kalliga, Kariva, Kimidess, Pimtrea, Reclipsen, Simliya, Velivet, Viorele, Volnea View more | Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, Curae, EContra One-Step, Fallback Solo, Her Style, Julie, Kyleena, Liletta, Mirena, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Optionelle, Plan B One-Step, PostDay One-Step, SheWise, Take Action View more | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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20 hours |
45 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 466 drugs are known to interact with Apri:
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A total of 255 drugs are known to interact with Skyla:
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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N/A |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.